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How to get fromNorth Charleston to Harrisburg, Paby plane, train, bus, bus (Greyhound, Flixbus), car, or train (Amtrak)

Find Transport to Harrisburg, Pa

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There are 7 ways to get from North Charleston to Harrisburg, Pa by plane, train, bus, bus (Greyhound, Flixbus), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charleston International Airport to Harrisburg International Airport

    best
    1. Fly from Charleston International Airport (CHS) to Harrisburg International Airport (MDT)plane plane CHS - MDT
    5h 34m
    $63–364

  2. Train, bus

    1. Take the train from Charleston Amtrak Station to Washington Union Stationtrain train Silver Meteor / ...
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus Greyhound US0430
    14h 1m
    $177–365

  3. Bus

    1. Take the bus from Charleston Bus Station to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus
    17h 8m
    $105–210

  4. Drive 605.5 mi

    1. Drive from North Charleston to Harrisburg, Pacar car 605.5 mi
    11h 29m
    $111–160

  5. Bus to Myrtle Beach, fly to Harrisburg International Airport

    1. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    2. Fly from Myrtle Beach (MYR) to Harrisburg International Airport (MDT)plane plane MYR - MDT
    5h 48m
    $77–354

  6. Fly Charleston International Airport to Philadelphia International Airport, train

    1. Fly from Charleston International Airport (CHS) to Philadelphia International Airport (PHL)plane plane CHS - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    6h 34m
    $365–975

  7. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to 30th Street Stationtrain train Palmetto / ...
    2. Take the train from 30th Street Station to Harrisburgtrain train Keystone Service / ...
    15h 25m
    $233–489

North Charleston to Harrisburg, Pa by train and bus

Calendar14Weekly Services
Duration14h 1mAverage Duration
Ticket$177Cheapest Price
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Questions & Answers

Map of how to get from North Charleston to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 550.4 mi
  • Duration: 5h 34m

What companies run services between North Charleston, SC, USA and Harrisburg, Pa, PA, USA?

United Airlines, American Airlines, and Delta fly from Charleston International Airport (CHS) to Harrisburg International Airport (MDT) hourly. Alternatively, you can take a bus from Charleston Bus Station to Harrisburg Bus Station via Raleigh Bus Station and Washington Union Station in around 17h 8m.

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