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How to get fromNorth Fort Myers to Charlestonby bus, plane, train, or car

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There are 7 ways to get from North Fort Myers to Charleston by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 140 bus, line 140 bus to Ft. Myers, fly

    best
    1. Take the bus from Cleveland Ave @ Hanck Brdg Pkwy-Sb to Rosa Parks Transportation Ctrbus bus
    2. Take the bus from Rosa Parks Transportation Ctr to South Fort Myers Transfer/P&Rbus bus
    3. Fly from Ft. Myers (RSW) to Charleston International Airport (CHS)plane plane RSW - CHS
    6h 49m
    $106–510

  2. Drive 528.3 mi

    cheapest
    1. Drive from North Fort Myers to Charlestoncar car 528.3 mi
    9h 33m
    $97–140

  3. Amtrak Thruway, train (Amtrak)

    1. Take the bus from Fort Myers, FL to Orlando, FLbus bus
    2. Take the train from Orlando to Charleston Amtrak Stationtrain train Silver Meteor
    16h 36m
    $215–399

  4. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    7h 47m
    $194–1,140

  5. Bus to Miami International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    8h 44m
    $528–1,050

  6. Bus to Tampa, fly

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    9h 43m
    $166–383

  7. Bus, train (Amtrak)

    1. Take the bus from Fort Myers Amtrak Bus Stop to Orlandobus bus Amtrak Thruway Connecting Service
    2. Take the train from Orlando to Charleston Amtrak Stationtrain train Silver Meteor
    16h 40m
    $221–400

Ft. Myers (RSW) to Charleston International Airport (CHS) flights

Calendar11Weekly Planes
Duration2h 20mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

Map of how to get from North Fort Myers to Charleston.ExpandLaunch map view
  • Distance: 486.4 mi
  • Duration: 6h 49m

What companies run services between North Fort Myers, FL, USA and Charleston, SC, USA?

There is no direct connection from North Fort Myers to Charleston. However, you can take the line 140 bus to Rosa Parks Transportation Ctr, take the line 140 bus to South Fort Myers Transfer/P&R, take the line 50 bus to Rsw, walk to Ft. Myers (RSW) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, then take the line 11 bus to Transit Mall. Alternatively, you can take a vehicle from North Fort Myers to Transit Mall via Fort Myers, FL, Orlando, FL, Orlando, Charleston Amtrak Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 16h 36m.

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