Rome2Rio

How to get fromNorth Fort Myers to Orangeburgby plane, taxi, bus (Flixbus), bus, train, or car

Find Transport to Orangeburg

See all options

There are 6 ways to get from North Fort Myers to Orangeburg by plane, taxi, bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia, taxi

    best
    1. Fly from Ft. Myers (RSW) to Columbia (CAE)plane plane RSW - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    8h 5m
    $344–1,358

  2. Drive 528.7 mi

    cheapest
    1. Drive from North Fort Myers to Orangeburgcar car 528.7 mi
    9h 46m
    $97–140

  3. Bus (Flixbus)

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Orangeburgbus bus FlixBus 2433
    14h 50m
    $104–183

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the train from Tampa to Denmark Amtrak Stationtrain train Floridian
    16h 34m
    $242–447

  5. Line 140 bus, fly to Charleston International Airport, line 104 bus, bus

    1. Take the bus from Rosa Parks Transportation Ctr to South Fort Myers Transfer/P&Rbus bus
    2. Fly from Ft. Myers (RSW) to Charleston International Airport (CHS)plane plane RSW - CHS
    3. Take the bus from N. Charleston SuperStop to North Charleston Transit Centerbus bus
    4. Take the bus from Charleston Bus Station to Orangeburgbus bus
    9h 45m
    $126–542

  6. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Ft. Myers (RSW) to Charlotte Douglas International Airport (CLT)plane plane RSW - CLT
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    11h 34m
    $162–724

Ft. Myers (RSW) to Columbia (CAE) flights

Calendar91Weekly Planes
Duration5h 20mAverage Duration
Ticket$225Cheapest Price
See schedules

Questions & Answers

Map of how to get from North Fort Myers to Orangeburg.ExpandLaunch map view
  • Distance: 574.3 mi
  • Duration: 8h 5m

What companies run services between North Fort Myers, FL, USA and Orangeburg, SC, USA?

You can take a bus from Cleveland Ave @ Hanck Brdg Pkwy-Sb to Orangeburg via Fort Myers Bus Stop, Orlando Bus Station, and Orangeburg in around 14h 50m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound