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How to get fromNorth Myrtle Beach to Buffaloby plane, bus (Greyhound, Flixbus), taxi, bus, train, car, or bus (Greyhound)

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There are 6 ways to get from North Myrtle Beach to Buffalo by plane, bus (Greyhound, Flixbus), taxi, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF)plane plane MYR - BUF
    3h 44m
    $161–694

  2. Drive  746.2 mi

    cheapest
    1. Drive from North Myrtle Beach to Buffalocar car 746.2 mi
    15h 20m
    $128–185

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Buffalobus bus
    23h 35m
    $226–341

  4. Taxi, bus, train

    1. Take the taxi from North Myrtle Beach to Whiteville Columbus County Transittaxi taxi
    2. Take the bus from Whiteville Columbus County Transit to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    24h 2m
    $675–1,005

  5. Fly to Rochester, bus

    1. Fly from Myrtle Beach (MYR) to Rochester (ROC)plane plane MYR - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 10m
    $151–478

  6. Bus via Raleigh

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Buffalobus bus
    24h 55m
    $243–546

Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) flights

Calendar39Weekly Planes
Duration3h 55mAverage Duration
Ticket$105Cheapest Price
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Comparing Your Travel Options

Map of how to get from North Myrtle Beach to Buffalo.ExpandLaunch map view
  • Distance: 667.4 mi
  • Duration: 3h 44m

What companies run services between North Myrtle Beach, SC, USA and Buffalo, NY, USA?

Breeze Airways, Southwest Airlines, and American Airlines fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a vehicle from North Myrtle Beach to Buffalo via Myrtle Beach Bus Station, Fayetteville Bus Station, and Newark Penn Station in around 23h 35m.

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