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How to get fromNorth Myrtle Beach to Buffaloby plane, taxi, bus, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)

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There are 8 ways to get from North Myrtle Beach to Buffalo by plane, taxi, bus, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF)plane plane MYR - BUF
    5h 19m
    $151–594

  2. Drive  745.8 mi

    cheapest
    1. Drive from North Myrtle Beach to Buffalocar car 745.8 mi
    15h 24m
    $137–197

  3. Taxi, bus, train

    1. Take the taxi from North Myrtle Beach to Whiteville Columbus County Transittaxi taxi
    2. Take the bus from Whiteville Columbus County Transit to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    24h 2m
    $384–756

  4. Bus

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to Buffalobus bus
    25h 5m
    $205–379

  5. Fly to Rochester, bus

    1. Fly from Myrtle Beach (MYR) to Rochester (ROC)plane plane MYR - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 13m
    $275–810

  6. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    27h 28m
    $363–775

  7. Bus, train via Fayetteville

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    30h 53m
    $358–766

  8. Bus via Columbus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    32h 30m
    $207–381

Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) flights

Calendar75Weekly Planes
Duration5h 1mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from North Myrtle Beach to Buffalo.ExpandLaunch map view
  • Distance: 667.4 mi
  • Duration: 5h 19m

What companies run services between North Myrtle Beach, SC, USA and Buffalo, NY, USA?

Southwest Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) every 2 hours. Alternatively, you can take a vehicle from North Myrtle Beach to Buffalo via Myrtle Beach Bus Station, Wilmington Cape Fear Public Transit, Raleigh Bus Station, and Newark Penn Station in around 25h 5m.

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