Rome2Rio

How to get fromNorth Myrtle Beach to Buffaloby plane, bus (Greyhound, Flixbus), taxi, bus, train, car, or bus (Greyhound)

Find Transport to Buffalo

See all options

There are 6 ways to get from North Myrtle Beach to Buffalo by plane, bus (Greyhound, Flixbus), taxi, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF)plane plane MYR - BUF
    5h 9m
    $161–644

  2. Drive  745.8 mi

    cheapest
    1. Drive from North Myrtle Beach to Buffalocar car 745.8 mi
    15h 24m
    $137–197

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Buffalobus bus
    23h 50m
    $218–341

  4. Taxi, bus, train

    1. Take the taxi from North Myrtle Beach to Whiteville Columbus County Transittaxi taxi
    2. Take the bus from Whiteville Columbus County Transit to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    24h 2m
    $404–864

  5. Fly to Rochester, bus

    1. Fly from Myrtle Beach (MYR) to Rochester (ROC)plane plane MYR - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 13m
    $215–857

  6. Bus via Columbus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to Buffalobus bus
    26h 30m
    $171–301

Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) flights

Calendar100Weekly Planes
Duration5h 4mAverage Duration
Ticket$99Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from North Myrtle Beach to Buffalo.ExpandLaunch map view
  • Distance: 667.4 mi
  • Duration: 5h 9m

What companies run services between North Myrtle Beach, SC, USA and Buffalo, NY, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from North Myrtle Beach to Buffalo via Myrtle Beach Bus Station, Raleigh Bus Station, and Newark Penn Station in around 23h 50m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There