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How to get fromNorthwestern University to St. Louisby train (Amtrak), bus (Flixbus), car, subway, plane, bus, or train

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There are 7 ways to get from Northwestern University to St. Louis by train (Amtrak), bus (Flixbus), car, subway, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 47m
    $96–198

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    8h 38m
    $52–88

  3. Drive 306.3 mi

    1. Drive from Northwestern University to St. Louiscar car 306.3 mi
    5h 20m
    $56–81

  4. Subway to Chicago O'Hare International Airport, fly

    1. Take the subway from Foster to Clark/Lakesubway subway
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    4h 30m
    $278–713

  5. Bus, train

    1. Take the bus from O'Hare Multi-Modal Facility to Uptown Stationbus bus 2-Southbound / ...
    2. Take the train from Bloomington-Normal to St. Louistrain train Lincoln Service / ...
    8h 58m
    $97–173

  6. Subway, subway to Chicago Midway International Airport, fly

    1. Take the subway from Foster to Clark/Lakesubway subway
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 23m
    $88–563

  7. Bus, bus to General Mitchell International Airport, fly

    1. Take the bus from Davis CTA Station to O'Hare MMF Bay 9bus bus
    2. Take the bus from Multi-Modal/Rental Car Facility to Mitchell Airportbus bus
    3. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    5h 57m
    $520–894

Northwestern University to St. Louis by foot, subway, bus, and train (Amtrak)

Calendar38Weekly Services
Duration6h 47mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Northwestern University to St. Louis.ExpandLaunch map view
  • Distance: 296.4 mi
  • Duration: 6h 47m

What companies run services between Northwestern University, IL, USA and St. Louis, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $90–190 and the journey takes 4h 46m. Alternatively, FlixBus-us operates a bus from Chicago Bus Station to St Louis Bus Station 3 times a day, and the journey takes 5h 55m. Flixbus USA also services this route twice daily.

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