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How to get fromNotre Dame to St. Louisby plane, train (Amtrak), bus (Greyhound), car, train, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Notre Dame to St. Louis by plane, train (Amtrak), bus (Greyhound), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from South Bend

    best
    1. Fly from South Bend (SBN) to Lambert–St. Louis International Airport (STL)plane plane SBN - STL
    4h 40m
    $123–676

  2. Drive 362.1 mi

    cheapest
    1. Drive from Notre Dame to St. Louiscar car 362.1 mi
    6h 10m
    $67–96

  3. Train (Amtrak)

    1. Take the train from South Bend Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    8h 3m
    $134–265

  4. Bus via Indianapolis

    1. Take the bus from South Street Station - South Bend to Indianapolis Union Stationbus bus South Bend
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    8h 8m
    $88–150

  5. Train to Chicago O'Hare International Airport, fly

    1. Take the train from South Bend Airport to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    6h 11m
    $308–747

  6. Train to Chicago Midway International Airport, fly

    1. Take the train from South Bend Airport to Van Buren St.train train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    5h 56m
    $118–597

  7. Train via South Bend Airport

    1. Take the train from South Bend Airport to Van Buren St.train train Westbound to Chicago / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    8h 18m
    $126–232

  8. Bus

    1. Take the bus from South Bend, IN to Chicagobus bus Columbus / ...
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    8h 48m
    $77–127

South Bend (SBN) to Lambert–St. Louis International Airport (STL) flights

Calendar97Weekly Planes
Duration5h 11mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Notre Dame to St. Louis.ExpandLaunch map view
  • Distance: 315.4 mi
  • Duration: 4h 40m

What companies run services between Notre Dame, IN, USA and St. Louis, MO, USA?

United Airlines, American Airlines, and Delta fly from South Bend (SBN) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Notre Dame to St. Louis via South Bend Station and Chicago Union Station in around 8h 3m.

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