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How to get fromNyon to Florenceby train (Trenitalia), bus, car, plane, or train

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There are 9 ways to get from Nyon to Florence by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Lausanne

    best
    1. Take the train from Lausanne to Domodossolatrain train Ec
    2. Take the train from Domodossola to Rho-Fiera Milanotrain train Re
    3. Take the train from Milano Rogoredo to Firenze Santa Maria Novellatrain train
    9h 8m
    €121–193

  2. Bus

    cheapest
    1. Take the bus from Nyon to Florence Villa Constanza Bus Stationbus bus
    10h
    €45–60

  3. Drive  628.5 km

    1. Drive from Nyon to Florencecar car 628.5 km
    6h 36m
    €132–190

  4. Fly Geneva International Airport to Florence Peretola Airport

    1. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    6h 14m
    €101–266

  5. Train

    1. Take the train from Nyon to Brigtrain train
    2. Take the train from Domodossola to Rho-Fiera Milanotrain train Re
    3. Take the train from Milano Rogoredo to Firenze Santa Maria Novellatrain train
    9h 18m
    €116–181

  6. Bus via Geneva

    1. Take the bus from Geneva to Florencebus bus FlixBus N1503
    10h 57m
    €62–139

  7. Fly Geneva International Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Geneva International Airport (GVA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane GVA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    6h 48m
    €89–245

  8. Train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Nyon to Zürich Flughafentrain train
    2. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    6h 44m
    €185–446

  9. Fly Geneva International Airport to Fiumicino International Airport, train

    1. Fly from Geneva International Airport (GVA) to Fiumicino International Airport (FCO)plane plane GVA - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    6h 36m
    €91–270

Nyon to Florence by bus

Calendar2Weekly Buses
Duration10hAverage Duration
Ticket€45Cheapest Price
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Comparing Your Travel Options

Map of how to get from Nyon to Florence.ExpandLaunch map view
  • Distance: 644.7 km
  • Duration: 9h 8m

What companies run services between Nyon, Switzerland and Florence, Italy?

You can take a train from Nyon to Firenze Santa Maria Novella via Lausanne, Domodossola, and Milano Rogoredo in around 9h 8m. Alternatively, Sellitto operates a bus from Nyon to Florence Villa Constanza Bus Station twice a week. Tickets cost €45–60 and the journey takes 10h.

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