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How to get fromO'Fallon to Detroitby train, plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

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There are 5 ways to get from O'Fallon to Detroit by train, plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly

    best
    1. Take the train from SHILOH-SCOTT station to LAMBERT AIRPORT TERMINAL #1 stationtrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane plane STL - DTW
    5h 27m
    $101–606

  2. Drive  507.9 mi

    cheapest
    1. Drive from O'Fallon to Detroitcar car 507.9 mi
    8h 52m
    $90–130

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Detroittrain train Wolverine
    13h 22m
    $304–484

  4. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Detroit Bus Stationbus bus Greyhound US0112
    13h 39m
    $99–154

  5. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from St Louis Bus Station to Chicagobus bus FlixBus N2521
    2. Take the bus from Chicago to Detroit Bus Stationbus bus FlixBus 2552
    15h 49m
    $99–159

O'Fallon to Detroit by bus and train (Amtrak)

Calendar21Weekly Services
Duration13h 22mAverage Duration
Ticket$304Cheapest Price
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Comparing Your Travel Options

Map of how to get from O'Fallon to Detroit.ExpandLaunch map view
  • Distance: 505.3 mi
  • Duration: 5h 27m

What companies run services between O'Fallon, IL, USA and Detroit, MI, USA?

You can take a bus from State @ Lincoln Eb to Detroit via Shiloh-Scott Transit Center, SHILOH-SCOTT station, CIVIC CENTER station, St. Louis, and Chicago Union Station in around 13h 22m. Alternatively, you can take a bus from State @ Cherry Wb to Detroit Bus Station via Fairview Heights Transit Center, FAIRVIEW HEIGHTS station, CIVIC CENTER station, St Louis Bus Station, and Indianapolis Union Station in around 13h 39m.

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Need to know: Greyhound

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