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How to get fromO'Fallon to Indianapolisby bus (Greyhound), car, train, or plane

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There are 3 ways to get from O'Fallon to Indianapolis by bus (Greyhound), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    6h 54m
    $44–69

  2. Drive  231.8 mi

    cheapest
    1. Drive from O'Fallon to Indianapoliscar car 231.8 mi
    4h 3m
    $43–62

  3. Train, fly

    1. Take the train from SHILOH-SCOTT station to LAMBERT AIRPORT TERMINAL #1 stationtrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Indianapolis (IND)plane plane STL - IND
    7h 15m
    $866–906

O'Fallon to Indianapolis by bus and train (Greyhound)

Calendar21Weekly Services
Duration6h 54mAverage Duration
Ticket$44Cheapest Price
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Comparing Your Travel Options

Map of how to get from O'Fallon to Indianapolis.ExpandLaunch map view
  • Distance: 266.3 mi
  • Duration: 6h 54m

What companies run services between O'Fallon, IL, USA and Indianapolis, IN, USA?

Greyhound USA operates a bus from St Louis Bus Station to Indianapolis Union Station 3 times a day. Tickets cost $40–65 and the journey takes 4h 45m.

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