Rome2Rio

How to get fromO'Hare to Des Moinesby plane, bus, car, subway, or train

Find Transport to Des Moines

See all options

There are 5 ways to get from O'Hare to Des Moines by plane, bus, car, subway, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    2h 46m
    $94–506
  2. Drive 326.3 mi

    cheapest
    1. Drive from O'Hare to Des Moinescar car 326.3 mi
    5h 29m
    $60–86
  3. Bus

    1. Take the bus from Chicago to Des Moinesbus bus Btw 1205 / ...
    8h 56m
    $82–125
  4. Subway, subway to Chicago Midway International Airport, fly

    1. Take the subway from Cumberland to Clark/Lakesubway subway
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane plane MDW - DSM
    3h 46m
    $122–681
  5. Train, bus

    1. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train Southwest Chief / ...
    2. Take the bus from Galesburg to Des Moinesbus bus Greyhound US0157S
    10h 18m
    $82–180

O'Hare to Des Moines by subway, foot, and bus

Calendar21Weekly Services
Duration8h 56mAverage Duration
Ticket$82Cheapest Price
See schedules

Questions & Answers

What companies run services between O'Hare, IL, USA and Des Moines, IA, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 3 hours. Alternatively, Jefferson Lines operates a bus from Chicago to Des Moines 3 times a day. Tickets cost $80–120 and the journey takes 7h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers