There are 6 ways to get from O'Hare to St. Louis by plane, train (Amtrak), bus (Flixbus), car, subway, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago O'Hare International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
3h 10m$326–708Bus (Flixbus)
cheapest- Take the bus from Chicago Bus Station to St Louis Bus Stationbus FlixBus 2510 / ...
7h 45m$47–79Train (Amtrak)
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
6h 35m$156–248Drive 296.6 mi
- Drive from O'Hare to St. Louiscar 296.6 mi
4h 59m$55–79Subway, subway to Chicago Midway International Airport, fly
- Take the subway from Cumberland to Clark/Lakesubway
- Take the subway from Clark/Lake to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
4h 8m$78–513Bus, train
- Take the bus from Multi-Modal Facility to Uptown Stationbus Peoria line
- Take the train from Bloomington-Normal to St. Louistrain Lincoln Service / ...
8h 17m$132–202
O'Hare to St. Louis by subway, foot, bus, and train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from O'Hare to St. Louis is to bus which costs $45 - $80 and takes 7h 45m.
The fastest way to get from O'Hare to St. Louis is to fly which takes 3h 10m and costs $320 - $750.
No, there is no direct bus from O'Hare to St. Louis station. However, there are services departing from Chicago and arriving at St Louis Bus Station via Chicago Bus Station. The journey, including transfers, takes approximately 7h 45m.
No, there is no direct train from O'Hare to St. Louis. However, there are services departing from Cumberland and arriving at St. Louis via Chicago Union Station. The journey, including transfers, takes approximately 6h 35m.
The distance between O'Hare and St. Louis is 278 miles. The road distance is 298.3 miles.
The best way to get from O'Hare to St. Louis without a car is to train which takes 6h 35m and costs $150 - $250.
It takes approximately 3h 10m to get from O'Hare to St. Louis, including transfers.
O'Hare to St. Louis bus services, operated by Flixbus USA, depart from Chicago Bus Station.
O'Hare to St. Louis train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from O'Hare to St. Louis is to fly which takes 3h 10m and costs $320 - $750. Alternatively, you can train, which costs $150 - $250 and takes 6h 35m, you could also bus, which costs $45 - $80 and takes 7h 45m.
What companies run services between O'Hare, IL, USA and St. Louis, MO, USA?
American Airlines, GoJet Airlines, and United Airlines fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $150–240 and the journey takes 4h 46m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $70–500
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $50–350
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $50–350
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $50–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Bloomington-Normal to St. Louis
- Ave. Duration
- 2h 45m
- Frequency
- 5 times a day
- Estimated price
- $85–140
- Website
- Amtrak
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Cumberland to Clark/Lake
- Ave. Duration
- 32 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Subway from Clark/Lake to Midway
- Ave. Duration
- 27 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
- Phone
- +1 800-448-0572
- [email protected]
- Website
- Peoria Charter
Bus from Multi-Modal Facility to Uptown Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $45–60
- Website
- Peoria Charter
- Schedules at
- Peoria Charter Schedules
- cash
- $60
- online
- $45
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
O'Hare to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
O'Hare to St. Louis train services, operated by Amtrak, arrive at St. Louis station.
Yes, the driving distance between O'Hare to St. Louis is 298 miles. It takes approximately 4h 59m to drive from O'Hare to St. Louis.
Book your O'Hare to St. Louis bus tickets online with Omio and FlixBus.
There are 571+ hotels available in St. Louis.