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How to get fromOak Brook to Charlestonby bus, plane, train (Amtrak), bus (Greyhound), or car

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There are 6 ways to get from Oak Brook to Charleston by bus, plane, train (Amtrak), bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 322 bus to Chicago Midway International Airport, fly to Charleston International Airport

    best
    1. Take the bus from 22nd St & Windsor Dr to 54th Ave CTA Station/Pink Linebus bus
    2. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane plane MDW - CHS
    6h 7m
    $107–558

  2. Train (Amtrak)

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    30h 23m
    $443–906

  3. Bus (Greyhound)

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    32h 39m
    $188–362

  4. Drive 879.8 mi

    1. Drive from Oak Brook to Charlestoncar car 879.8 mi
    16h 9m
    $161–232

  5. Bus to Chicago O'Hare International Airport, fly to Charleston International Airport

    1. Take the bus from Oakbrook Mall to O'Hare International Terminal 2bus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane plane ORD - CHS
    6h 38m
    $124–474

  6. Bus to Chicago O'Hare International Airport, fly to Hilton Head Airport, drive

    1. Take the bus from Oakbrook Mall to O'Hare International Terminal 2bus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Hilton Head Airport (HHH)plane plane ORD - HHH
    3. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    7h 22m
    $135–479

Oak Brook to Charleston by bus, subway, and foot (Greyhound)

Calendar7Weekly Services
Duration32h 39mAverage Duration
Ticket$188Cheapest Price
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Questions & Answers

Map of how to get from Oak Brook to Charleston.ExpandLaunch map view
  • Distance: 778 mi
  • Duration: 6h 7m

What companies run services between Oak Brook, IL, USA and Charleston, SC, USA?

You can take a vehicle from Oak Brook to Charleston via Western Springs, Chicago Union Station, Petersburg Amtrak Station, and Charleston Amtrak Station in around 30h 23m. Alternatively, you can take a bus from York Rd & 22nd St to Transit Mall via Forest Park CTA Station, Forest Park, LaSalle, Chicago Train Station, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 32h 39m.

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