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How to get fromOcala to Des Moinesby taxi, plane, bus (Amtrak, Flixbus, Greyhound), bus, train, car, or shuttle

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There are 6 ways to get from Ocala to Des Moines by taxi, plane, bus (Amtrak, Flixbus, Greyhound), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Gainesville Regional Airport, fly

    best
    1. Take the taxi from Ocala to Gainesville-Airport-GNVtaxi taxi
    2. Fly from Gainesville Regional Airport (GNV) to Des Moines (DSM)plane plane GNV - DSM
    5h 32m
    $261–667

  2. Drive to Orlando Sanford, fly

    cheapest
    1. Drive from Ocala to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    4h 49m
    $131–531

  3. Bus

    1. Take the bus from Ocala Amtrak Bus Stop to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    43h 59m
    $300–480

  4. Bus, train

    1. Take the bus from Ocala Amtrak Bus Stop to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    46h 31m
    $489–1,027

  5. Drive  1,245.1 mi

    1. Drive from Ocala to Des Moinescar car 1,245.1 mi
    21h 40m
    $228–329

  6. Shuttle to Orlando, fly

    1. Take a shuttle bus from Hiton Garden Inn Downtown Ocala to Orlando Airportshuttle bus
    2. Fly from Orlando (MCO) to Des Moines (DSM)plane plane MCO - DSM
    7h 56m
    $182–551

Ocala to Des Moines by bus

Calendar7Weekly Buses
Duration43h 59mAverage Duration
Ticket$300Cheapest Price
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Questions & Answers

Map of how to get from Ocala to Des Moines.ExpandLaunch map view
  • Distance: 1,084.6 mi
  • Duration: 5h 32m

What companies run services between Ocala, FL, USA and Des Moines, IA, USA?

You can take a bus from Ocala Amtrak Bus Stop to Des Moines via Jacksonville, Amtrak Station, JRTC Bay H, Jacksonville, Washington Union Station, and Chicago Bus Station in around 43h 59m.

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