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How to get fromOcean Springs to Knoxvilleby plane, train, bus, taxi, shuttle, or car

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There are 4 ways to get from Ocean Springs to Knoxville by plane, train, bus, taxi, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS)plane plane GPT - TYS
    4h 15m
    $261–1,125

  2. Drive  559.9 mi

    cheapest
    1. Drive from Ocean Springs to Knoxvillecar car 559.9 mi
    9h 12m
    $96–139

  3. Train, bus, taxi, shuttle, drive

    1. Take the train from Biloxi, MS to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Boonebus bus
    4. Take the taxi from Boone to Black Bear Resorttaxi taxi
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Knoxvillecar car
    34h 43m
    $786–1,149

  4. Fly to Asheville Regional Airport, drive

    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Asheville Regional Airport (AVL)plane plane GPT - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 24m
    $126–445

Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS) flights

Calendar54Weekly Planes
Duration4h 57mAverage Duration
Ticket$165Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ocean Springs to Knoxville.ExpandLaunch map view
  • Distance: 504.8 mi
  • Duration: 4h 15m

What companies run services between Ocean Springs, MS, USA and Knoxville, TN, USA?

Delta, American Airlines, and United Airlines fly from Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS) every 4 hours.

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