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How to get fromOdessa to St. Louisby plane, bus (Greyhound), bus, train, or car

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There are 5 ways to get from Odessa to St. Louis by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Midland International Airport (MAF) to Lambert–St. Louis International Airport (STL)plane plane MAF - STL
    4h 54m
    $157–643

  2. Bus

    1. Take the bus from Stripes gas station - Odessa, TX to Big Springbus bus
    2. Take the bus from Big Spring to Amarillo Multimodal Transfer Stabus bus
    3. Take the bus from Amarillo Multimodal Transfer Sta to St Louis Bus Stationbus bus
    22h 12m
    $188–344

  3. Bus, train

    1. Take the bus from Stripes gas station - Odessa, TX to Fort Worth - La Gran Plazabus bus Dallas
    2. Take the train from Fort Worth to St. Louistrain train Texas Eagle
    23h 41m
    $304–582

  4. Drive 928.2 mi

    1. Drive from Odessa to St. Louiscar car 928.2 mi
    15h 36m
    $170–245

  5. Bus, train via Fort Worth

    1. Take the bus from Odessa, TX - Stripes Gas Station to Fort Worth, TX - Tornado Bus Cobus bus El Paso
    2. Take the train from Fort Worth to St. Louistrain train Texas Eagle
    23h 56m
    $302–665

Midland International Airport (MAF) to Lambert–St. Louis International Airport (STL) flights

Calendar84Weekly Planes
Duration4h 58mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Odessa to St. Louis.ExpandLaunch map view
  • Distance: 841 mi
  • Duration: 4h 54m

What companies run services between Odessa, TX, USA and St. Louis, MO, USA?

Southwest Airlines, American Airlines, and United Airlines fly from Midland International Airport (MAF) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a bus from Stripes gas station - Odessa, TX to St Louis Bus Station via Big Spring and Amarillo Multimodal Transfer Sta in around 22h 12m.

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