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How to get fromOhio to Cairoby bus, taxi, train, car, or plane

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There are 9 ways to get from Ohio to Cairo by bus, taxi, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Columbus to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    13h 2m
    $167–231

  2. Drive  452.8 mi

    cheapest
    1. Drive from Columbus to Cairocar car 452.8 mi
    7h 41m
    $83–120

  3. Bus, train, taxi

    1. Take the bus from Columbus to Toledobus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Carbondaletrain train
    4. Take the taxi from Carbondale to Cairotaxi taxi
    15h 49m
    $434–656

  4. Fly John Glenn Columbus International Airport to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    7h 52m
    $903–1,030

  5. Bus, taxi via Nashville

    1. Take the bus from Columbus to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    15h 5m
    $172–244

  6. Fly Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    7h 42m
    $594–1,030

  7. Fly John Glenn Columbus International Airport to Nashville, bus, taxi

    1. Fly from John Glenn Columbus International Airport (CMH) to Nashville (BNA)plane plane CMH - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    8h 1m
    $909–1,245

  8. Fly Cleveland-Hopkins International Airport to Nashville, bus, taxi

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Nashville (BNA)plane plane CLE - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    7h 51m
    $240–434

  9. Fly Covington to Nashville, bus, taxi

    1. Fly from Covington (CVG) to Nashville (BNA)plane plane CVG - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    8h 5m
    $1,011–1,146

John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) flights

Calendar22Weekly Planes
Duration2h 45mAverage Duration
Ticket$93Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ohio to Cairo.ExpandLaunch map view
  • Distance: 568.7 mi
  • Duration: 13h 2m

What companies run services between Ohio, USA and Cairo, IL, USA?

There is no direct connection from Ohio to Cairo. However, you can take the bus to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Cairo. Alternatively, you can take the bus to Toledo, walk to Toledo, take the train to Chicago Union Station, take the train to Carbondale, then take the taxi to Cairo.

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