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How to get fromOhio to Cairoby bus, taxi, car, plane, or train

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There are 9 ways to get from Ohio to Cairo by bus, taxi, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi via Louisville

    best
    1. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    2. Take the bus from Louisville, KY to Nashvillebus bus
    3. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    4. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    12h 50m
    $157–255

  2. Drive 452.8 mi

    cheapest
    1. Drive from Columbus to Cairocar car 452.8 mi
    7h 41m
    $83–120

  3. Fly John Glenn Columbus International Airport to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    7h 52m
    $903–1,036

  4. Bus, taxi

    1. Take the bus from Columbus to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    13h 2m
    $167–258

  5. Bus, train, taxi

    1. Take the bus from Columbus to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    4. Take the train from Champaign-Urbana to Fulton Amtrak Stationtrain train
    5. Take the taxi from Fulton Amtrak Station to Cairotaxi taxi
    14h 14m
    $248–435

  6. Fly Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    7h 42m
    $594–1,036

  7. Fly John Glenn Columbus International Airport to Nashville, bus, taxi

    1. Fly from John Glenn Columbus International Airport (CMH) to Nashville (BNA)plane plane CMH - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    8h 1m
    $910–1,150

  8. Fly Cleveland-Hopkins International Airport to Nashville, bus, taxi

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Nashville (BNA)plane plane CLE - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    7h 51m
    $196–440

  9. Fly Covington to Nashville, bus, taxi

    1. Fly from Covington (CVG) to Nashville (BNA)plane plane CVG - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    8h 5m
    $1,062–1,151

John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) flights

Calendar32Weekly Planes
Duration2h 42mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

Map of how to get from Ohio to Cairo.ExpandLaunch map view
  • Distance: 561.7 mi
  • Duration: 12h 50m

What companies run services between Ohio, USA and Cairo, IL, USA?

There is no direct connection from Ohio to Cairo. However, you can take the bus to Louisville, KY Bus Station, take the bus to Nashville, take the bus to Paducah Bus Station, then take the taxi to Cairo. Alternatively, you can drive from Columbus to Cairo in around 7h 41m.

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