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How to get fromOhio to Cape Girardeauby plane, bus, bus (Greyhound), or car

Find Transport to Cape Girardeau

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There are 8 ways to get from Ohio to Cape Girardeau by plane, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Glenn Columbus International Airport to Lambert–St. Louis International Airport, bus

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 4m
    $830–950

  2. Drive 460.1 mi

    cheapest
    1. Drive from Columbus to Cape Girardeaucar car 460.1 mi
    8h 13m
    $84–122

  3. Bus via Indianapolis

    1. Take the bus from Columbus to Indianapolisbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    11h 48m

  4. Fly Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 54m
    $520–950

  5. Bus to Detroit, fly to Lambert–St. Louis International Airport, bus

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    8h 38m
    $511–1,042

  6. Fly Dayton to Cape Girardeau Municipal Airport

    1. Fly from Dayton (DAY) to Cape Girardeau Municipal Airport (CGI)plane plane DAY - CGI
    8h 38m
    $195–780

  7. Fly John Glenn Columbus International Airport to Cape Girardeau Municipal Airport

    1. Fly from John Glenn Columbus International Airport (CMH) to Cape Girardeau Municipal Airport (CGI)plane plane CMH - CGI
    6h 38m
    $185–731

  8. Bus

    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    12h 14m
    $92–170

John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) flights

Calendar32Weekly Planes
Duration2h 42mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

Map of how to get from Ohio to Cape Girardeau.ExpandLaunch map view
  • Distance: 551.1 mi
  • Duration: 7h 4m

What companies run services between Ohio, USA and Cape Girardeau, MO, USA?

You can take a bus from Columbus to Cape Girardeau via Indianapolis, Indianapolis Union Station, St Louis Bus Station, and Cape Girardeau in around 11h 48m. Alternatively, United Airlines, Corporate Flight Management Inc, and American Airlines fly from Dayton (DAY) to Cape Girardeau Municipal Airport (CGI) twice daily.

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