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How to get fromOhio to Cape Girardeauby plane, bus, bus (Greyhound), car, train, or taxi

Find Transport to Cape Girardeau

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There are 6 ways to get from Ohio to Cape Girardeau by plane, bus, bus (Greyhound), car, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport, bus

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 4m
    $829–943

  2. Drive  460.1 mi

    cheapest
    1. Drive from Columbus to Cape Girardeaucar car 460.1 mi
    8h 13m
    $84–122

  3. Bus (Greyhound)

    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    12h 14m
    $90–140

  4. Fly from Cleveland-Hopkins International Airport, bus

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 54m
    $520–942

  5. Bus to Detroit, fly, bus

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    8h 38m
    $702–1,024

  6. Bus, train, taxi

    1. Take the bus from Columbus to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    4. Take the train from Champaign-Urbana to Carbondaletrain train
    5. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    12h 14m
    $185–313

John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) flights

Calendar40Weekly Planes
Duration2h 59mAverage Duration
Ticket$95Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ohio to Cape Girardeau.ExpandLaunch map view
  • Distance: 551.1 mi
  • Duration: 7h 4m

What companies run services between Ohio, USA and Cape Girardeau, MO, USA?

You can take a bus from Columbus to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 12h 14m.

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