There are 7 ways to get from Ohio to Cape Girardeau by plane, bus, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly John Glenn Columbus International Airport to Lambert–St. Louis International Airport, bus
best- Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane CMH - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
7h 14m$133–700Drive 460.1 mi
cheapest- Drive from Columbus to Cape Girardeaucar 460.1 mi
8h 13m$79–114Bus (Greyhound)
- Take the bus from Columbus to St Louis Bus Stationbus Greyhound US0421
- Take the bus from St Louis Bus Station to Cape Girardeaubus Greyhound US1173
12h 34m$106–159Fly Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport, bus
- Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane CLE - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
7h 4m$134–700Bus to Detroit, fly to Lambert–St. Louis International Airport, bus
- Take the bus from Toledo to Dearbornbus
- Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane DTW - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
8h 43mFly John Glenn Columbus International Airport to Cape Girardeau Municipal Airport
- Fly from John Glenn Columbus International Airport (CMH) to Cape Girardeau Municipal Airport (CGI)plane CMH - CGI
6h 45m$175–781Fly Covington to Cape Girardeau Municipal Airport
- Fly from Covington (CVG) to Cape Girardeau Municipal Airport (CGI)plane CVG - CGI
7h 16m$217–932
John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from Ohio to Cape Girardeau is to drive which costs $75 - $120 and takes 8h 13m.
The fastest way to get from Ohio to Cape Girardeau is to fly which takes 6h 45m and costs $170 - $800.
No, there is no direct bus from Ohio to Cape Girardeau. However, there are services departing from Columbus and arriving at Cape Girardeau via St Louis Bus Station. The journey, including transfers, takes approximately 12h 34m.
The distance between Ohio and Cape Girardeau is 554 miles. The road distance is 462.8 miles.
The best way to get from Ohio to Cape Girardeau without a car is to bus which takes 12h 34m and costs $100 - $160.
It takes approximately 7h 14m to get from Ohio to Cape Girardeau, including transfers.
Ohio to Cape Girardeau bus services, operated by Greyhound USA, depart from Columbus station.
The best way to get from Ohio to Cape Girardeau is to bus which takes 12h 34m and costs $100 - $160. Alternatively, you can fly, which costs $170 - $800 and takes 6h 45m.
Ohio to Cape Girardeau bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Cape Girardeau is 1h behind Ohio. It is currently 3:03 PM in Ohio and 2:03 PM in Cape Girardeau.
What companies run services between Ohio, USA and Cape Girardeau, MO, USA?
You can take a bus from Columbus to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 12h 34m. Alternatively, United Airlines, Corporate Flight Management Inc, and American Airlines fly from John Glenn Columbus International Airport (CMH) to Cape Girardeau Municipal Airport (CGI) twice daily.
- Website
- southwest.com
Flights from John Glenn Columbus International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $100–650
Flights from John Glenn Columbus International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $110–700
Flights from John Glenn Columbus International Airport to Lambert–St. Louis International Airport via Kansas City
- Ave. Duration
- 3h 55m
- When
- Sunday
- Estimated price
- $150–800
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $100–650
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $110–650
Flights from Detroit to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $120–750
Flights from Detroit to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 32m
- When
- Tuesday and Wednesday
- Estimated price
- $120–750
- Website
- delta.com
Flights from John Glenn Columbus International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $120–700
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $110–650
Flights from Detroit to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $120–750
- Website
- united.com
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $110–650
Flights from Detroit to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $130–800
- Website
- contouraviation.com
Flights from John Glenn Columbus International Airport to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $300–950
Flights from John Glenn Columbus International Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 26m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from Covington to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $360–1,200
Flights from Covington to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–900
Flights from Covington to Cape Girardeau Municipal Airport via Orlando Sanford
- Ave. Duration
- 8h 10m
- When
- Wednesday
- Estimated price
- $800–2,300
- Website
- aa.com
Flights from Detroit to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–800
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from Columbus to St Louis Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- Every 4 hours
- Estimated price
- $75–120
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $21–35
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Toledo to Dearborn
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Website
- Amtrak
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Booking & Getting There
Yes, the driving distance between Ohio to Cape Girardeau is 463 miles. It takes approximately 8h 13m to drive from Ohio to Cape Girardeau.
There are 23+ hotels available in Cape Girardeau.







