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How to get fromOhio to Greenvilleby plane, bus (Greyhound), car, or bus

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There are 6 ways to get from Ohio to Greenville by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Greenville–Spartanburg International Airport (GSP)plane plane CMH - GSP
    3h 25m
    $137–698

  2. Drive 437.7 mi

    cheapest
    1. Drive from Columbus to Greenvillecar car 437.7 mi
    9h 38m
    $80–116

  3. Bus

    1. Take the bus from Columbus - Mound St to Charlotte Bus Stationbus bus Columbus
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus Charlotte
    14h 19m
    $126–295

  4. Line 46 bus to Covington, fly

    1. Take the bus from Vine St & Hollister St to Government Square Area Dbus bus
    2. Fly from Covington (CVG) to Greenville–Spartanburg International Airport (GSP)plane plane CVG - GSP
    3h 42m
    $159–749

  5. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Greenville–Spartanburg International Airport (GSP)plane plane DTW - GSP
    5h 16m
    $177–740

  6. Bus via N Murray Hill Rd & Beacon Hill Rd

    1. Take the bus from Wilson & Ferrell Shell Station - Columbus to Charlotte Bus Stationbus bus Greyhound US0140
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus Charlotte
    18h 6m
    $134–318

John Glenn Columbus International Airport (CMH) to Greenville–Spartanburg International Airport (GSP) flights

Calendar17Weekly Planes
Duration3hAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from Ohio to Greenville.ExpandLaunch map view
  • Distance: 379.6 mi
  • Duration: 3h 25m

What companies run services between Ohio, USA and Greenville, SC, USA?

Breeze Airways, American Airlines, and Delta fly from John Glenn Columbus International Airport (CMH) to Greenville–Spartanburg International Airport (GSP) twice daily. Alternatively, you can take a bus from Columbus - Mound St to Greenville via Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & Dorton St, Charlotte, and Taqueria Guadalajara - Greenville in around 14h 19m.

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