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How to get fromOhio to Iowaby bus, plane, bus (Flixbus, Greyhound), car, bus (Greyhound), or train

Find Transport to Iowa

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There are 10 ways to get from Ohio to Iowa by bus, plane, bus (Flixbus, Greyhound), car, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Detroit, fly to Des Moines

    best
    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 20m
    $171–766

  2. Fly John Glenn Columbus International Airport to Quad City International Airport

    cheapest
    1. Fly from John Glenn Columbus International Airport (CMH) to Quad City International Airport (MLI)plane plane CMH - MLI
    7h 2m
    $74–435

  3. Bus

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    15h 5m
    $114–202

  4. Drive 620.1 mi

    1. Drive from Columbus to Des Moinescar car 620.1 mi
    11h 27m
    $114–164

  5. Fly Dayton to Quad City International Airport

    1. Fly from Dayton (DAY) to Quad City International Airport (MLI)plane plane DAY - MLI
    6h 57m
    $79–454

  6. Fly Cleveland-Hopkins International Airport to Quad City International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Quad City International Airport (MLI)plane plane CLE - MLI
    6h 44m
    $80–444

  7. Bus to Detroit, fly to Omaha

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Omaha (OMA)plane plane DTW - OMA
    5h 40m
    $159–625

  8. Fly Covington to Quad City International Airport

    1. Fly from Covington (CVG) to Quad City International Airport (MLI)plane plane CVG - MLI
    7h 14m
    $76–426

  9. Bus via Indianapolis (Greyhound)

    1. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    15h 10m
    $106–204

  10. Bus, train

    1. Take the bus from Columbus - Mound St to Toledobus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    18h 4m
    $184–381

Detroit (DTW) to Des Moines (DSM) flights

Calendar68Weekly Planes
Duration3h 33mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Ohio to Iowa.ExpandLaunch map view
  • Distance: 623.1 mi
  • Duration: 5h 20m

What companies run services between Ohio, USA and Iowa, USA?

You can take a bus from Columbus to Des Moines via Chicago Bus Station and Des Moines in around 15h 5m. Alternatively, United Airlines, Delta, and American Airlines fly from Dayton (DAY) to Quad City International Airport (MLI) every 3 hours.

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