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How to get fromOhio to La Crosseby plane, bus, train, car, or bus (Flixbus)

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There are 9 ways to get from Ohio to La Crosse by plane, bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Cleveland-Hopkins International Airport

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to La Crosse (LSE)plane plane CLE - LSE
    6h 9m
    $96–476

  2. Fly from Dayton

    cheapest
    1. Fly from Dayton (DAY) to La Crosse (LSE)plane plane DAY - LSE
    6h 9m
    $76–375

  3. Bus, train

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    13h 38m
    $126–251

  4. Bus, train via Toledo

    1. Take the bus from Columbus to Toledobus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    14h 17m
    $155–348

  5. Drive  591.6 mi

    1. Drive from Columbus to La Crossecar car 591.6 mi
    10h 54m
    $108–156

  6. Fly from John Glenn Columbus International Airport

    1. Fly from John Glenn Columbus International Airport (CMH) to La Crosse (LSE)plane plane CMH - LSE
    6h 13m
    $96–486

  7. Fly from Covington

    1. Fly from Covington (CVG) to La Crosse (LSE)plane plane CVG - LSE
    6h 37m
    $103–517

  8. Bus

    1. Take the bus from Columbus to Milwaukee Intermodal Stationbus bus FlixBus 2511
    2. Take the bus from Milwaukee to La Crossebus bus Jefferson Lines 966
    14h 40m
    $113–176

  9. Bus via LaPorte

    1. Take the bus from Columbus - Mound St to La Porte, INbus bus
    2. Take the bus from La Porte, IN to Chicagobus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to La Crossebus bus
    16h 45m
    $96–222

Ohio to La Crosse by bus, foot, and train

Calendar15Weekly Services
Duration13h 38mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from Ohio to La Crosse.ExpandLaunch map view
  • Distance: 527 mi
  • Duration: 6h 9m

What companies run services between Ohio, USA and La Crosse, WI, USA?

United Airlines and American Airlines fly from Cleveland-Hopkins International Airport (CLE) to La Crosse (LSE) every 4 hours. Alternatively, you can take a bus from Columbus to La Crosse via Milwaukee Intermodal Station and Milwaukee in around 14h 40m.

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