There are 9 ways to get from Ohio to La Crosse by plane, bus, train, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John Glenn Columbus International Airport
best- Fly from John Glenn Columbus International Airport (CMH) to La Crosse (LSE)plane CMH - LSE
6h 50m$101–516Fly from Dayton
cheapest- Fly from Dayton (DAY) to La Crosse (LSE)plane DAY - LSE
6h 58m$76–375Bus, train
- Take the bus from Columbus to Chicago Bus Stationbus FlixBus 2511 / ...
- Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain Empire Builder / ...
13h 38m$209–326Bus, train via Toledo
- Take the bus from Columbus to Toledo Bus Stopbus
- Take the train from Toledo to Chicago Union Stationtrain
- Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain
14h 52m$283–488Drive 591.6 mi
- Drive from Columbus to La Crossecar 591.6 mi
10h 54m$102–147Fly from Cleveland-Hopkins International Airport
- Fly from Cleveland-Hopkins International Airport (CLE) to La Crosse (LSE)plane CLE - LSE
5h 42m$102–496Fly from Covington
- Fly from Covington (CVG) to La Crosse (LSE)plane CVG - LSE
6h 21m$123–677Bus
- Take the bus from Columbus to Milwaukee Intermodal Stationbus FlixBus 2511
- Take the bus from Milwaukee to La Crossebus Jefferson Lines 966
14h 40m$123–182Bus via Chicago
- Take the bus from Columbus to Chicagobus
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to La Crossebus
15h 25m$93–187
Ohio to La Crosse by bus, foot, and train
Comparing Your Travel Options
The cheapest way to get from Ohio to La Crosse is to drive which costs $100 - $150 and takes 10h 54m.
The fastest way to get from Ohio to La Crosse is to fly which takes 5h 42m and costs $100 - $500.
No, there is no direct bus from Ohio to La Crosse. However, there are services departing from Columbus and arriving at La Crosse via Milwaukee. The journey, including transfers, takes approximately 14h 40m.
The distance between Ohio and La Crosse is 530 miles. The road distance is 595.1 miles.
The best way to get from Ohio to La Crosse without a car is to bus and train which takes 13h 38m and costs $200 - $330.
It takes approximately 6h 50m to get from Ohio to La Crosse, including transfers.
Ohio to La Crosse bus services, operated by Flixbus USA, depart from Columbus station.
The best way to get from Ohio to La Crosse is to fly which takes 6h 50m and costs $100 - $550. Alternatively, you can bus, which costs $120 - $190 and takes 14h 40m.
Ohio to La Crosse bus services, operated by Flixbus USA, arrive at Milwaukee Intermodal Station.
La Crosse is 1h behind Ohio. It is currently 9:10 AM in Ohio and 8:10 AM in La Crosse.
What companies run services between Ohio, USA and La Crosse, WI, USA?
American Airlines and United Airlines fly from John Glenn Columbus International Airport (CMH) to La Crosse (LSE) 5 times a day. Alternatively, you can take a bus from Columbus to La Crosse via Milwaukee Intermodal Station and Milwaukee in around 14h 40m.
- Website
- aa.com
Flights from John Glenn Columbus International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $80–490
Flights from Cleveland-Hopkins International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $80–470
Flights from Dayton to La Crosse via Chicago O'Hare
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $55–350
Flights from Dayton to La Crosse via Reagan Washington, Chicago O'Hare
- Ave. Duration
- 9h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
Flights from Dayton to La Crosse via Charlotte, Chicago O'Hare
- Ave. Duration
- 9h 32m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $100–480
Flights from Covington to La Crosse via Chicago O'Hare
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $100–650
- Website
- allegiantair.com
Flights from Dayton to La Crosse via Punta Gorda
- Ave. Duration
- 8h 10m
- When
- Sunday and Thursday
- Estimated price
- $160–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to La Crosse Amtrak Station
- Ave. Duration
- 4h 59m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Toledo to Chicago Union Station
- Ave. Duration
- 4h 23m
- Frequency
- 3 times a day
- Estimated price
- $120–200
- Website
- Amtrak
Train from Chicago Union Station to La Crosse Amtrak Station
- Ave. Duration
- 4h 59m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Columbus to Chicago Bus Station
- Ave. Duration
- 7h 30m
- Frequency
- 4 times a day
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
Bus from Columbus to Milwaukee Intermodal Station
- Ave. Duration
- 10h
- Frequency
- Twice daily
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to Toledo Bus Stop
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Columbus to Toledo Bus Stop
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $13–50
- Website
- Barons Bus
Bus from Columbus to Chicago
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Barons Bus
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to La Crosse
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Madison to La Crosse
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Ohio to La Crosse is 595 miles. It takes approximately 10h 54m to drive from Ohio to La Crosse.
There are 46+ hotels available in La Crosse.














