Rome2Rio

How to get fromOhio to Saint Charlesby plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

Find Transport to Saint Charles

See all options

There are 9 ways to get from Ohio to Saint Charles by plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Cleveland-Hopkins International Airport

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    4h 5m
    $496–906

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from Columbus to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    10h 35m
    $66–108

  3. Drive  430.4 mi

    1. Drive from Columbus to Saint Charlescar car 430.4 mi
    7h 17m
    $79–114

  4. Fly from John Glenn Columbus International Airport, line 34 bus

    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    2. Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus bus
    4h 20m
    $806–907

  5. Fly from Dayton

    1. Fly from Dayton (DAY) to Lambert–St. Louis International Airport (STL)plane plane DAY - STL
    6h 42m
    $86–486

  6. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 29m
    $608–958

  7. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    5h 54m
    $632–993

  8. Bus to Pittsburgh International Airport, fly

    1. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    6h 39m
    $114–620

  9. Bus (Greyhound)

    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    10h 53m
    $68–106

Ohio to Saint Charles by bus and train

Calendar10Weekly Services
Duration10h 35mAverage Duration
Ticket$66Cheapest Price
See schedules

Questions & Answers

Map of how to get from Ohio to Saint Charles.ExpandLaunch map view
  • Distance: 512.4 mi
  • Duration: 4h 5m

What companies run services between Ohio, USA and Saint Charles, MO, USA?

Southwest Airlines, Delta, and United Airlines fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Columbus to 4375 Rider Trail North Sb via Dayton Trotwood Bus Station, Indianapolis Union Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 10h 35m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers