There are 8 ways to get from Ohio to Winston-Salem by bus (Greyhound), car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Columbus to Winston Salem(Trans Center)bus Greyhound US0140
9h 20m$75–120Drive 368.4 mi
cheapest- Drive from Columbus to Winston-Salemcar 368.4 mi
6h 37m$68–98Bus to Detroit, fly to Piedmont Triad International Airport
- Take the bus from Toledo to Dearbornbus
- Fly from Detroit (DTW) to Piedmont Triad International Airport (GSO)plane DTW - GSO
6h 6mFly John Glenn Columbus International Airport to Charlotte Douglas International Airport, bus
- Fly from John Glenn Columbus International Airport (CMH) to Charlotte Douglas International Airport (CLT)plane CMH - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 31m$129–780Fly Cleveland-Hopkins International Airport to Charlotte Douglas International Airport, bus
- Fly from Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT)plane CLE - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 21m$130–730Fly Dayton to Charlotte Douglas International Airport, bus
- Fly from Dayton (DAY) to Charlotte Douglas International Airport (CLT)plane DAY - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 40m$104–579Fly Akron to Charlotte Douglas International Airport, bus
- Fly from Akron (CAK) to Charlotte Douglas International Airport (CLT)plane CAK - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 24m$104–565Fly Covington to Charlotte Douglas International Airport, bus
- Fly from Covington (CVG) to Charlotte Douglas International Airport (CLT)plane CVG - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 51m$151–931
Ohio to Winston-Salem by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Ohio to Winston-Salem is to drive which costs $65 - $100 and takes 6h 37m.
The fastest way to get from Ohio to Winston-Salem is to fly and bus which takes 6h 21m and costs $130 - $750.
Yes, there is a direct bus departing from Columbus and arriving at Winston Salem(Trans Center). Services depart once daily, and operate every day. The journey takes approximately 9h 20m.
The distance between Ohio and Winston-Salem is 421 miles. The road distance is 370.5 miles.
The best way to get from Ohio to Winston-Salem without a car is to bus which takes 9h 20m and costs $75 - $120.
The bus from Columbus to Winston Salem(Trans Center) takes 9h 20m including transfers and departs once daily.
Ohio to Winston-Salem bus services, operated by Greyhound USA, depart from Columbus station.
Ohio to Winston-Salem bus services, operated by Greyhound USA, arrive at Winston Salem(Trans Center) station.
Yes, the driving distance between Ohio to Winston-Salem is 371 miles. It takes approximately 6h 37m to drive from Ohio to Winston-Salem.
Book your Ohio to Winston-Salem bus tickets online with Omio and FlixBus.
What companies run services between Ohio, USA and Winston-Salem, NC, USA?
Greyhound USA operates a bus from Columbus to Winston Salem(Trans Center) once daily. Tickets cost $75–120 and the journey takes 9h 20m.
- Website
- aa.com
Flights from Detroit to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $95–550
Flights from Detroit to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 4h 16m
- When
- Saturday
- Estimated price
- $100–600
Flights from John Glenn Columbus International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $110–750
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $110–700
Flights from Dayton to Charlotte Douglas International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $85–550
Flights from Dayton to Charlotte Douglas International Airport via Reagan Washington
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $110–650
Flights from Akron to Charlotte Douglas International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $85–550
Flights from Covington to Charlotte Douglas International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $130–900
- Website
- delta.com
Flights from Detroit to Piedmont Triad International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $85–550
Flights from Detroit to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $120–650
Flights from Dayton to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $110–650
Flights from Covington to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $170–1,000
- Website
- united.com
Flights from Detroit to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $100–600
Flights from Dayton to Charlotte Douglas International Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $110–650
- Website
- southwest.com
Flights from John Glenn Columbus International Airport to Charlotte Douglas International Airport via Baltimore
- Ave. Duration
- 3h 55m
- When
- Saturday
- Estimated price
- $150–900
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Saturday
- Estimated price
- $140–800
Flights from Covington to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Sunday, Thursday, and Friday
- Estimated price
- $160–1,000
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $13–21
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Toledo to Dearborn
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Website
- Amtrak
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Booking & Getting There
There are 152+ hotels available in Winston-Salem.







