Rome2Rio

How to get fromOklahoma City to Kirksvilleby bus, train, car, plane, or shuttle

Find Transport to Kirksville

See all options

There are 6 ways to get from Oklahoma City to Kirksville by bus, train, car, plane, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Oklahoma City Bus Station to Kansas City Bus Stationbus bus Greyhound US0136S / ...
    2. Take the train from Kansas City to La Plata Stationtrain train Southwest Chief
    11h 2m
    $139–253

  2. Drive 507 mi

    cheapest
    1. Drive from Oklahoma City to Kirksvillecar car 507 mi
    8h 37m
    $93–134

  3. Bus, train via Newton (Amtrak)

    1. Take the bus from Oklahoma City to Newton Stationbus bus Amtrak Thruway Connecting Service
    2. Take the train from Newton Station to La Plata Stationtrain train Southwest Chief
    12h 12m
    $209–375

  4. Fly Will Rogers World Airport to Columbia Regional Airport, shuttle

    1. Fly from Will Rogers World Airport (OKC) to Columbia Regional Airport (COU)plane plane OKC - COU
    2. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    7h 19m
    $167–554

  5. Fly Will Rogers World Airport to Kirksville Regional Airport

    1. Fly from Will Rogers World Airport (OKC) to Kirksville Regional Airport (IRK)plane plane OKC - IRK
    5h 25m
    $163–628

  6. Drive to Stillwater Regional Airport, fly to Kirksville Regional Airport

    1. Drive from Oklahoma City to Stillwater Regional Airport (SWO)car car
    2. Fly from Stillwater Regional Airport (SWO) to Kirksville Regional Airport (IRK)plane plane SWO - IRK
    6h 46m
    $157–612

Will Rogers World Airport (OKC) to Columbia Regional Airport (COU) flights

Calendar52Weekly Planes
Duration6h 4mAverage Duration
Ticket$85Cheapest Price
See schedules

Questions & Answers

Map of how to get from Oklahoma City to Kirksville.ExpandLaunch map view
  • Distance: 516.7 mi
  • Duration: 11h 2m

What companies run services between Oklahoma City, OK, USA and Kirksville, MO, USA?

American Airlines and Corporate Flight Management Inc fly from Will Rogers World Airport (OKC) to Kirksville Regional Airport (IRK) twice daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound