Rome2Rio

How to get fromOld Lyme to Hyannisby train, bus, car, or bus (Greyhound, Flixbus)

Find Transport to Hyannis

See all options

There are 4 ways to get from Old Lyme to Hyannis by train, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from New London to Bostontrain train Northeast Regional
    2. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus Hyannis - South Shore to Logan Airport
    5h 59m
    $84–127
  2. Drive  136.6 mi

    cheapest
    1. Drive from Old Lyme to Hyanniscar car 136.6 mi
    2h 48m
    $25–36
  3. Train, bus via Boston

    1. Take the train from New London to Bostontrain train Northeast Regional
    2. Take the bus from Boston to Hyannisbus bus Bz 0956 / ...
    6h 11m
    $71–117
  4. Bus

    1. Take the bus from Old Saybrook Trans Cntr to Asylum St @ Union Plbus bus 921
    2. Take the bus from Hartford Union Station to Bostonbus bus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    7h 37m
    $44–67

Old Lyme to Hyannis by bus and train

Calendar30Weekly Services
Duration5h 59mAverage Duration
Ticket$84Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Old Lyme, CT, USA and Hyannis, MA, USA?

You can take a bus from Lyme St & Library Ln to Hyannis Transportation Center via Old Saybrook Train Station Bus Shelter, Old Saybrook Trans Cntr, Asylum St @ Union Pl, Hartford Union Station, Boston, and Boston South Buses in around 7h 37m.

Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides