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How to get fromOld Lyme to Syracuseby bus (Greyhound, Flixbus), train (Amtrak), car, train, plane, or bus

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There are 9 ways to get from Old Lyme to Syracuse by bus (Greyhound, Flixbus), train (Amtrak), car, train, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Old Saybrook Trans Cntr to Asylum St @ Union Plbus bus 921
    2. Take the bus from Hartford to Springfieldbus bus
    3. Take the bus from Springfield Union Station to Syracuse Bus Stationbus bus
    9h 33m
    $37–85

  2. Train (Amtrak)

    1. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Syracuse Regional Transportation Centertrain train Empire Service / ...
    10h 11m
    $118–260

  3. Drive 267.5 mi

    1. Drive from Old Lyme to Syracusecar car 267.5 mi
    5h 59m
    $49–71

  4. Train, train to Laguardia Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Old Saybrook Amtrak Station to Stamford Amtrak Stationtrain train
    2. Take the train from Stamford to 125th Street - Harlemtrain train
    3. Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane plane LGA - SYR
    8h 14m
    $126–729

  5. Train, bus

    1. Take the train from Old Saybrook Amtrak Station to New Haventrain train
    2. Take the train from New Haven to Grand Central Terminaltrain train
    3. Take the bus from New York to Syracusebus bus
    9h 50m
    $68–225

  6. Train via Albany

    1. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Albany-Rensselaer Amtrak Stationtrain train
    3. Take the train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Centertrain train
    10h 44m
    $113–355

  7. Train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane plane JFK - SYR
    8h 21m
    $118–597

  8. Train to Boston Logan Airport, fly to Syracuse Hancock International Airport

    1. Take the train from New London to Bostontrain train
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    8h 2m
    $122–639

  9. Train, train to Laguardia Airport, fly to Rochester

    1. Take the train from Old Saybrook Amtrak Station to Stamford Amtrak Stationtrain train
    2. Take the train from Stamford to 125th Street - Harlemtrain train
    3. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    4. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    9h 5m
    $169–913

Old Lyme to Syracuse by bus

Calendar17Weekly Buses
Duration9h 33mAverage Duration
Ticket$37Cheapest Price
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Questions & Answers

Map of how to get from Old Lyme to Syracuse.ExpandLaunch map view
  • Distance: 302.3 mi
  • Duration: 9h 33m

What companies run services between Old Lyme, CT, USA and Syracuse, NY, USA?

You can take a bus from Lyme St & Library Ln to Syracuse Bus Station via Old Saybrook Train Station Bus Shelter, Old Saybrook Trans Cntr, Asylum St @ Union Pl, Hartford, Springfield, and Springfield Union Station in around 9h 33m. Alternatively, you can take a bus from Lyme St & Library Ln to Syracuse Regional Transportation Center via Stage Rd & Route 1, Old Saybrook Amtrak Station, and Ny Moynihan Train Hall At Penn Station in around 10h 11m.

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