There are 7 ways to get from Omaha to La Crosse by plane, bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Omaha to La Crosse
best- Fly from Omaha (OMA) to La Crosse (LSE)plane OMA - LSE
5h 41m$90–424Drive 370.7 mi
cheapest- Drive from Omaha to La Crossecar 370.7 mi
7h 14m$66–95Bus, train
- Take the bus from Omaha, NE to Des Moinesbus
- Take the bus from Des Moines to Minneapolis Bus Stationbus
- Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain
12h 7m$142–220Drive to Lincoln Municipal Airport, fly to La Crosse
- Drive from Omaha to Lincoln-Airport-LNKcar
- Fly from Lincoln Municipal Airport (LNK) to La Crosse (LSE)plane LNK - LSE
7h 6m$99–428Fly Omaha to Minneapolis–Saint Paul International Airport, train
- Fly from Omaha (OMA) to Minneapolis–Saint Paul International Airport (MSP)plane OMA - MSP
- Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain
7h 2m$138–544Fly Omaha to Rochester, bus
- Fly from Omaha (OMA) to Rochester (RST)plane OMA - RST
- Take the bus from Rochester to La Crossebus
8h 24m$85–431Bus
- Take the bus from Omaha, NE to Des Moinesbus
- Take the bus from Des Moines to Minneapolis Bus Stationbus
- Take the bus from Minneapolis to La Crossebus
12h 50m$115–172
Omaha to La Crosse by bus and train
Comparing Your Travel Options
The cheapest way to get from Omaha to La Crosse is to drive which costs $65 - $95 and takes 7h 14m.
The fastest way to get from Omaha to La Crosse is to fly which takes 5h 41m and costs $90 - $430.
No, there is no direct bus from Omaha to La Crosse. However, there are services departing from Omaha, NE and arriving at La Crosse via Des Moines and Minneapolis. The journey, including transfers, takes approximately 12h 50m.
The distance between Omaha and La Crosse is 309 miles. The road distance is 372.8 miles.
The best way to get from Omaha to La Crosse without a car is to bus and train which takes 12h 7m and costs $140 - $220.
It takes approximately 5h 41m to get from Omaha to La Crosse, including transfers.
Omaha to La Crosse bus services, operated by Greyhound USA, depart from Omaha, NE station.
The best way to get from Omaha to La Crosse is to fly which takes 5h 41m and costs $90 - $430. Alternatively, you can bus, which costs $110 - $180 and takes 12h 50m.
Omaha to La Crosse bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between Omaha to La Crosse is 373 miles. It takes approximately 7h 14m to drive from Omaha to La Crosse.
What companies run services between Omaha, NE, USA and La Crosse, WI, USA?
American Airlines and United Airlines fly from Omaha (OMA) to La Crosse (LSE) 4 times a day. Alternatively, you can take a bus from Omaha, NE to La Crosse via Des Moines and Minneapolis in around 12h 50m.
- Website
- aa.com
Flights from Omaha to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $70–400
Flights from Lincoln Municipal Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 7h 16m
- When
- Every day
- Estimated price
- $70–390
Flights from Lincoln Municipal Airport to La Crosse via Dallas/Ft.Worth, Chicago O'Hare
- Ave. Duration
- 11h 7m
- When
- Every day
- Estimated price
- $120–550
Flights from Omaha to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $75–410
- Website
- delta.com
Flights from Omaha to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $65–430
Flights from Omaha to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $55–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Paul-Minneapolis to La Crosse Amtrak Station
- Ave. Duration
- 2h 47m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Amtrak
Train from St. Paul-Minneapolis to La Crosse Amtrak Station
- Ave. Duration
- 2h 47m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Des Moines to Minneapolis Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Des Moines to Minneapolis Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $45–70
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to La Crosse
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Minneapolis to La Crosse
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $45–65
- Book at
- Jefferson Lines
- Adult
- $45–65
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 46+ hotels available in La Crosse.









