What is the cheapest way to get from Omaha to Mayo Clinic Hospital?

The cheapest way to get from Omaha to Mayo Clinic Hospital is to drive which costs $60 - $90 and takes 5h 41m.

What is the fastest way to get from Omaha to Mayo Clinic Hospital?

The fastest way to get from Omaha to Mayo Clinic Hospital is to fly and bus which takes 5h 34m and costs $600 - $1,000.

Is there a direct bus between Omaha and Mayo Clinic Hospital?

No, there is no direct bus from Omaha to Mayo Clinic Hospital. However, there are services departing from Omaha, NE and arriving at Rochester via Des Moines and St. Paul. The journey, including transfers, takes approximately 11h 36m.

How far is it from Omaha to Mayo Clinic Hospital?

The distance between Omaha and Mayo Clinic Hospital is 459 miles. The road distance is 341.9 miles.

How do I travel from Omaha to Mayo Clinic Hospital without a car?

The best way to get from Omaha to Mayo Clinic Hospital without a car is to bus which takes 11h 36m and costs $80 - $150.

How long does it take to get from Omaha to Mayo Clinic Hospital?

It takes approximately 11h 36m to get from Omaha to Mayo Clinic Hospital, including transfers.

Where do I catch the Omaha to Mayo Clinic Hospital bus from?

Omaha to Mayo Clinic Hospital bus services, operated by Greyhound USA, depart from Omaha, NE station.

Bus or fly from Omaha to Mayo Clinic Hospital?

The best way to get from Omaha to Mayo Clinic Hospital is to bus which takes 11h 36m and costs $80 - $150. Alternatively, you can fly, which costs $60 - $440 and takes 7h 3m.

Where does the Omaha to Mayo Clinic Hospital bus arrive?

Omaha to Mayo Clinic Hospital bus services, operated by Greyhound USA, arrive at Des Moines station.

Can I drive from Omaha to Mayo Clinic Hospital?

Yes, the driving distance between Omaha to Mayo Clinic Hospital is 342 miles. It takes approximately 5h 41m to drive from Omaha to Mayo Clinic Hospital.

Where can I stay near Mayo Clinic Hospital?

There are 75+ hotels available in Mayo Clinic Hospital.

Omaha to Mayo Clinic Hospital - 5 ways to travel via bus, car, and plane

How to get fromOmaha to Mayo Clinic Hospital

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There are 5 ways to get from Omaha to Mayo Clinic Hospital by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Omaha, NE to Des Moinesbus
2. Take the bus from Des Moines to Saint Paul Union Depotbus
3. Take the bus from St. Paul to Rochesterbus
11h 36m
$83–148
Drive 339.9 mi
cheapest
1. Drive from Omaha to Mayo Clinic Hospitalcar 339.9 mi
5h 41m
$62–90
Fly to Rochester
1. Fly from Omaha (OMA) to Rochester (RST)plane OMA - RST
7h 3m
$62–431
Bus via Sioux Falls
1. Take the bus from Omaha to Sioux Fallsbus
2. Take the bus from Sioux Falls to Minneapolis-St. Paulbus
3. Take the bus from Minneapolis / St Paul Airport to Rochester Hotelsbus
15h 41m
$178–233
Fly to Minneapolis–Saint Paul International Airport, bus
1. Fly from Omaha (OMA) to Minneapolis–Saint Paul International Airport (MSP)plane OMA - MSP
2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 34m
$603–1,003

Omaha (OMA) to Rochester (RST) flights

37Weekly Planes

4h 55mAverage Duration

$63Cheapest Price

See schedules

Questions & Answers

Map of how to get from Omaha to Mayo Clinic Hospital.

Launch map view

Distance: 456.5 mi
Duration: 11h 36m

What companies run services between Omaha, NE, USA and Mayo Clinic Hospital, MN, USA?

You can take a bus from Omaha, NE to Mayo Clinic Hospital via Des Moines, St. Paul, and Rochester in around 11h 36m. Alternatively, American Airlines, Delta, and United Airlines fly from Omaha (OMA) to Rochester (RST) 5 times a day.

Airlines

Bus operators

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How to get fromOmaha to Mayo Clinic Hospitalby bus (Greyhound), car, plane, or bus

There are 5 ways to get from Omaha to Mayo Clinic Hospital by bus (Greyhound), car, plane, or bus

Bus

Drive 339.9 mi

Fly to Rochester

Bus via Sioux Falls

Fly to Minneapolis–Saint Paul International Airport, bus