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How to get fromOpelika to Knoxvilleby taxi, plane, bus, shuttle, or car

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There are 4 ways to get from Opelika to Knoxville by taxi, plane, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Columbus Airport, fly

    best
    1. Take the taxi from Opelika to Columbus Airport (CSG)taxi taxi
    2. Fly from Columbus Airport (CSG) to Mcghee Tyson Airport (TYS)plane plane CSG - TYS
    4h 5m
    $246–1,004

  2. Drive  285.6 mi

    cheapest
    1. Drive from Opelika to Knoxvillecar car 285.6 mi
    5h 30m
    $49–71

  3. Bus, shuttle, drive

    1. Take the bus from Opelika 4th Street Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Boonebus bus
    4. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Knoxvillecar car
    17h 49m
    $311–367

  4. Bus to Hartsfield-Jackson Atlanta International Airport, fly

    1. Take the bus from Fairfield Inn & Suites Opelika to Atlanta Airportbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Mcghee Tyson Airport (TYS)plane plane ATL - TYS
    3h 57m
    $224–1,045

Columbus Airport (CSG) to Mcghee Tyson Airport (TYS) flights

Calendar17Weekly Planes
Duration3h 30mAverage Duration
Ticket$124Cheapest Price
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Comparing Your Travel Options

Map of how to get from Opelika to Knoxville.ExpandLaunch map view
  • Distance: 277.7 mi
  • Duration: 4h 5m

What companies run services between Opelika, AL, USA and Knoxville, TN, USA?

There is no direct connection from Opelika to Knoxville. However, you can take the taxi to Columbus Airport (CSG) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a bus from Opelika 4th Street Station to Knoxville via Atlanta Bus Station, Charlotte, Boone, Boone, Black Bear Resort, and Hot Springs in around 17h 49m.

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