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How to get fromOpelousas to Destinby bus, taxi, train, car, or plane

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There are 9 ways to get from Opelousas to Destin by bus, taxi, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Lafayette to Crestviewbus bus Houston
    2. Take the taxi from Crestview to Destintaxi taxi
    7h 44m
    $171–223

  2. Drive 361.3 mi

    cheapest
    1. Drive from Opelousas to Destincar car 361.3 mi
    6h 28m
    $66–96

  3. Train, bus, taxi

    1. Take the train from Lafayette Amtrak Station to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    3. Take the bus from Mobile to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    12h 13m
    $211–363

  4. Fly Lafayette Regional Airport to Destin–Fort Walton Beach Airport

    1. Fly from Lafayette Regional Airport (LFT) to Destin–Fort Walton Beach Airport (VPS)plane plane LFT - VPS
    5h 12m
    $126–468

  5. Bus, taxi via Biloxi

    1. Take the bus from Lafayette to Biloxi Transit Centerbus bus
    2. Take the bus from Biloxi to Crestviewbus bus
    3. Take the taxi from Crestview to Destintaxi taxi
    9h 33m
    $181–248

  6. Bus, train, taxi

    1. Take the bus from Opelousas to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    3. Take the bus from Mobile to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    12h 15m
    $194–323

  7. Fly Lafayette Regional Airport to Northwest Florida Beaches International Airport, taxi

    1. Fly from Lafayette Regional Airport (LFT) to Northwest Florida Beaches International Airport (ECP)plane plane LFT - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    5h 56m
    $226–583

  8. Fly Lafayette Regional Airport to Pensacola International Airport, taxi

    1. Fly from Lafayette Regional Airport (LFT) to Pensacola International Airport (PNS)plane plane LFT - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    5h 35m
    $196–523

  9. Bus to Alexandria International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Opelousas to Boyce, LAbus bus
    2. Fly from Alexandria International Airport (AEX) to Destin–Fort Walton Beach Airport (VPS)plane plane AEX - VPS
    7h 13m
    $158–504

Lafayette Regional Airport (LFT) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar45Weekly Planes
Duration5h 29mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Opelousas to Destin.ExpandLaunch map view
  • Distance: 468 mi
  • Duration: 7h 44m

What companies run services between Opelousas, LA, USA and Destin, FL, USA?

Delta and American Airlines fly from Lafayette Regional Airport (LFT) to Destin–Fort Walton Beach Airport (VPS) every 4 hours.

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