Rome2Rio

How to get fromOpelousas to Mobileby bus, train, car, plane, bus (Greyhound, Flixbus), or train (Amtrak)

Find Transport to Mobile

See all options

There are 9 ways to get from Opelousas to Mobile by bus, train, car, plane, bus (Greyhound, Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Lafayette to Mobilebus bus Houston
    5h 13m
    $76–103

  2. Drive  258.1 mi

    cheapest
    1. Drive from Opelousas to Mobilecar car 258.1 mi
    4h 22m
    $48–68

  3. Bus, train via Baton Rouge

    1. Take the bus from Opelousas to Baton Rouge Bus Stationbus bus
    2. Take the bus from Baton Rouge Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    7h 19m
    $62–128

  4. Fly from Lafayette Regional Airport

    1. Fly from Lafayette Regional Airport (LFT) to Mobile Regional Airport (MOB)plane plane LFT - MOB
    4h 57m
    $106–443

  5. Bus via Baton Rouge

    1. Take the bus from Opelousas to Baton Rouge Bus Stationbus bus Greyhound 2221 / ...
    2. Take the bus from Baton Rouge Bus Station to Mobile Bus Stationbus bus Greyhound US0602 / ...
    6h 33m
    $49–78

  6. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to New Orleans Union Passenger Terminaltrain train Sunset Limited
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train Amtrak Mardi Gras Service / ...
    8h 32m
    $76–178

  7. Bus, train

    1. Take the bus from Opelousas to New Orleans Bus Stationbus bus Greyhound 2221 / ...
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train Amtrak Mardi Gras Service / ...
    8h 34m
    $70–143

  8. Bus to Alexandria International Airport, fly

    1. Take the bus from Opelousas to Boyce, LAbus bus
    2. Fly from Alexandria International Airport (AEX) to Mobile Regional Airport (MOB)plane plane AEX - MOB
    7h 19m
    $138–476

  9. Bus to Lake Charles Regional Airport, fly

    1. Take the bus from Lafayette to Lake Charlesbus bus
    2. Fly from Lake Charles Regional Airport (LCH) to Mobile Regional Airport (MOB)plane plane LCH - MOB
    6h 56m
    $152–496

Lafayette Regional Airport (LFT) to Mobile Regional Airport (MOB) flights

Calendar76Weekly Planes
Duration5h 27mAverage Duration
Ticket$68Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Opelousas to Mobile.ExpandLaunch map view
  • Distance: 319.8 mi
  • Duration: 5h 13m

What companies run services between Opelousas, LA, USA and Mobile, AL, USA?

Omnibus Express operates a bus from Lafayette to Mobile once daily. Tickets cost $65–90 and the journey takes 4h 49m. Alternatively, United Airlines, Delta, and American Airlines fly from Lafayette Regional Airport (LFT) to Mobile Regional Airport (MOB) every 2 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There