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How to get fromOrange County to Key West (Island)by plane, bus, ferry, train, car, or bus (Greyhound, Flixbus)

Find Transport to Key West (Island)

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There are 7 ways to get from Orange County to Key West (Island) by plane, bus, ferry, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Key West International Airport (EYW)plane plane SNA - EYW
    7h 15m
    $179–634

  2. Train to San Diego International Airport, fly

    cheapest
    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to Key West International Airport (EYW)plane plane SAN - EYW
    10h 29m
    $158–608

  3. Bus, ferry

    1. Take the bus from Santa Ana to El Pasobus bus Cbx
    2. Take the bus from El Paso Bus Station to Houston Bus Stationbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    2d 11h
    $577–794

  4. Train, bus, ferry

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Fort Myersbus bus
    5. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    2d 21h
    $932–1,808

  5. Drive 2,815.6 mi

    1. Drive from Orange County to Key Westcar car 2,815.6 mi
    47h 11m
    $514–743

  6. Train to Los Angeles International Airport, fly

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Key West International Airport (EYW)plane plane LAX - EYW
    9h 55m
    $568–936

  7. Bus

    1. Take the bus from Santa Ana Bus Stop to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Key West Airportbus bus
    2d 22h
    $460–909

Orange County to Key West (Island) by bus

Calendar28Weekly Buses
Duration2d 22hAverage Duration
Ticket$460Cheapest Price
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Questions & Answers

Map of how to get from Orange County to Key West (Island).ExpandLaunch map view
  • Distance: 2,261.9 mi
  • Duration: 7h 15m

What companies run services between Orange County, CA, USA and Key West (Island), FL, USA?

American Airlines and Delta fly from John Wayne Airport Orange County (SNA) to Key West International Airport (EYW) 3 times a day. Alternatively, you can take a bus from Santa Ana Bus Stop to Key West Airport via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, and Miami Airport Station in around 2d 22h.

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