What is the cheapest way to get from Orange County to Otay Mesa?

The cheapest way to get from Orange County to Otay Mesa is to drive which costs $19 - $28 and takes 1h 53m.

What is the fastest way to get from Orange County to Otay Mesa?

The fastest way to get from Orange County to Otay Mesa is to drive which takes 1h 53m and costs $19 - $28.

Is there a direct bus between Orange County and Otay Mesa?

No, there is no direct bus from Orange County to Otay Mesa. However, there are services departing from Santa Ana and arriving at Otay Mesa Rd & Cactus Rd via San Ysidro Bl & Virginia Av and Iris Avenue Transit Center. The journey, including transfers, takes approximately 3h 5m.

Is there a direct train between Orange County and Otay Mesa?

No, there is no direct train from Orange County to Otay Mesa station. However, there are services departing from Santa Ana and arriving at Iris Avenue Station via Old Town Station. The journey, including transfers, takes approximately 3h 14m.

How far is it from Orange County to Otay Mesa?

The distance between Orange County and Otay Mesa is 113 miles. The road distance is 106 miles.

How do I travel from Orange County to Otay Mesa without a car?

The best way to get from Orange County to Otay Mesa without a car is to bus which takes 3h 5m and costs $25 - $45.

How long does it take to get from Orange County to Otay Mesa?

It takes approximately 3h 5m to get from Orange County to Otay Mesa, including transfers.

Where do I catch the Orange County to Otay Mesa bus from?

Orange County to Otay Mesa bus services, operated by Greyhound Mexico, depart from Santa Ana station.

Where do I catch the Orange County to Otay Mesa train from?

Orange County to Otay Mesa train services, operated by Amtrak, depart from Santa Ana station.

Where does the Orange County to Otay Mesa bus arrive?

Orange County to Otay Mesa bus services, operated by Greyhound Mexico, arrive at San Ysidro station.

Where does the Orange County to Otay Mesa train arrive?

Orange County to Otay Mesa train services, operated by Amtrak, arrive at San Diego Old Town Transportation Center station.

Can I drive from Orange County to Otay Mesa?

Yes, the driving distance between Orange County to Otay Mesa is 106 miles. It takes approximately 1h 53m to drive from Orange County to Otay Mesa.

Where can I stay near Otay Mesa?

There are 561+ hotels available in Otay Mesa.

Orange County to Otay Mesa - 4 ways to travel via train, bus, tram, and car

How to get fromOrange County to Otay Mesa

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There are 4 ways to get from Orange County to Otay Mesa by bus (Greyhound), train, tram, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus (Greyhound)
best
1. Take the bus from Santa Ana to San Ysidrobus Los Angeles
3h 5m
$25–42
Bus, tram
cheapest
1. Take the bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stopbus Greyhound US0831
2. Take the tram from Old Town Station to Iris Avenue Stationtram Blue
3h 8m
$17–41
Train, tram
1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain Pacific Surfliner
2. Take the tram from Old Town Station to Iris Avenue Stationtram Blue
3h 14m
$31–74
Drive 105.4 mi
1. Drive from Orange County to Otay Mesacar 105.4 mi
1h 53m
$20–28

Orange County to Otay Mesa by bus (Greyhound)

21Weekly Buses

3h 5mAverage Duration

$25Cheapest Price

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Questions & Answers

Map of how to get from Orange County to Otay Mesa.

Launch map view

Distance: 112.1 mi
Duration: 3h 5m

What companies run services between Orange County, CA, USA and Otay Mesa, CA, USA?

Greyhound Mexico operates a bus from Santa Ana to San Ysidro 3 times a day. Tickets cost $21–35 and the journey takes 2h 20m.

Train operators

Bus operators

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