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How to get fromOrangeburg to Buffaloby bus, plane, train (Amtrak), car, bus (Flixbus), or train

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There are 10 ways to get from Orangeburg to Buffalo by bus, plane, train (Amtrak), car, bus (Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Western Hwy & Orangeburg Rd to Port Authority Bus Terminalbus bus
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    5h 21m
    $107–656

  2. Drive 352.6 mi

    cheapest
    1. Drive from Orangeburg to Buffalocar car 352.6 mi
    6h 56m
    $65–93

  3. Train

    1. Take the train from Croton-Harmon Amtrak Station to Buffalotrain train Empire Service / ...
    9h 35m
    $138–317

  4. Bus

    1. Take the bus from Western Hwy & Orangeburg Rd to Port Authority Bus Terminalbus bus Rockland Coaches
    2. Take the bus from New York to Buffalobus bus Adt N816 / ...
    10h 19m
    $72–304

  5. Bus to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Western Hwy & Orangeburg Rd to Port Authority Bus Terminalbus bus
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    5h 24m
    $98–532

  6. Bus, bus to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Western Hwy & Orangeburg Rd to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    5h 34m
    $109–548

  7. Bus to Laguardia Airport, fly to Rochester, bus

    1. Take the bus from Western Hwy & Orangeburg Rd to Port Authority Bus Terminalbus bus
    2. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 2m
    $139–720

  8. Bus, bus to Newark Liberty International Airport, fly to Rochester

    1. Take the bus from Western Hwy & Orangeburg Rd to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    3. Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane plane EWR - ROC
    4. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 16m
    $536–1,692

  9. Bus via New York

    1. Take the bus from Western Hwy & Orangeburg Rd to Port Authority Bus Terminalbus bus Rockland Coaches
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus N2686 / ...
    10h 54m
    $77–134

  10. Bus, train

    1. Take the bus from Western Hwy & Orangeburg Rd to Port Authority Bus Terminalbus bus Rockland Coaches
    2. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    10h 55m
    $122–314

Orangeburg to Buffalo by bus

Calendar45Weekly Buses
Duration10h 19mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Orangeburg to Buffalo.ExpandLaunch map view
  • Distance: 376 mi
  • Duration: 5h 21m

What companies run services between Orangeburg, NY, USA and Buffalo, NY, USA?

Amtrak operates a train from Croton-Harmon Amtrak Station to Buffalo 3 times a day. Tickets cost $120–270 and the journey takes 7h 54m. VIA Rail also services this route once daily. Alternatively, you can take a bus from Western Hwy & Orangeburg Rd to Buffalo via Port Authority Bus Terminal and New York in around 10h 19m.

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