There are 6 ways to get from Orangeburg to Chicago by taxi, plane, bus (Flixbus, Greyhound, Amtrak), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Columbia, fly to Chicago O'Hare International Airport
best- Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi
- Fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD)plane CAE - ORD
3h 57m$177–453Drive to Charleston International Airport, fly to Chicago Midway International Airport
cheapest- Drive from Orangeburg to Charleston-Airport-CHScar
- Fly from Charleston International Airport (CHS) to Chicago Midway International Airport (MDW)plane CHS - MDW
4h 3m$100–483Bus
- Take the bus from Orangeburg to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Toledo Bus Stopbus
- Take the bus from Toledo to Chicago Union Stationbus
22h 35mTrain (Amtrak)
- Take the train from Denmark Amtrak Station to Chicago Union Stationtrain Floridian
31h 13m$768–1,280Drive 801.8 mi
- Drive from Orangeburg to Chicagocar 801.8 mi
14h 47m$147–212Drive to Charleston International Airport, fly to Chicago O'Hare International Airport
- Drive from Orangeburg to Charleston-Airport-CHScar
- Fly from Charleston International Airport (CHS) to Chicago O'Hare International Airport (ORD)plane CHS - ORD
4h 28m$565–823
Columbia (CAE) to Chicago O'Hare International Airport (ORD) flights
Comparing Your Travel Options
The cheapest way to get from Orangeburg to Chicago is to drive which costs $140 - $220 and takes 14h 47m.
The fastest way to get from Orangeburg to Chicago is to taxi and fly which takes 3h 57m and costs $170 - $460.
No, there is no direct bus from Orangeburg to Chicago station. However, there are services departing from Orangeburg and arriving at Chicago Union Station via Charlotte Bus Station and Toledo. The journey, including transfers, takes approximately 22h 35m.
No, there is no direct train from Orangeburg station to Chicago station. However, there are services departing from Denmark Amtrak Station and arriving at Chicago Union Station via . The journey, including transfers, takes approximately 31h 13m.
The distance between Orangeburg and Chicago is 728 miles. The road distance is 806.5 miles.
The best way to get from Orangeburg to Chicago without a car is to bus which takes 22h 35m and costs .
It takes approximately 3h 57m to get from Orangeburg to Chicago, including transfers.
Orangeburg to Chicago bus services, operated by Flixbus USA, depart from Orangeburg station.
Orangeburg to Chicago train services, operated by Amtrak, depart from Denmark Amtrak Station.
The best way to get from Orangeburg to Chicago is to bus which takes 22h 35m and costs . Alternatively, you can train, which costs $750 - $1,300 and takes 31h 13m.
What companies run services between Orangeburg, SC, USA and Chicago, IL, USA?
You can take a vehicle from Orangeburg to Chicago Union Station via Orangeburg, Charlotte Bus Station, and Toledo in around 22h 35m. Alternatively, Amtrak operates a train from Denmark Amtrak Station to Chicago Union Station once daily. Tickets cost $700–1,200 and the journey takes 30h 41m.
- Website
- aa.com
Flights from Columbia to Chicago O'Hare International Airport
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- $50–300
Flights from Columbia to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $55–300
Flights from Columbia to Chicago O'Hare International Airport via Reagan Washington
- Ave. Duration
- 5h 7m
- When
- Monday to Saturday
- Estimated price
- $70–350
Flights from Charleston International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $65–370
Flights from Charleston International Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $65–370
- Website
- united.com
Flights from Columbia to Chicago O'Hare International Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $50–300
Flights from Columbia to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $65–350
Flights from Charleston International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 34m
- When
- Every day
- Estimated price
- $65–370
- Website
- delta.com
Flights from Columbia to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $60–320
Flights from Charleston International Airport to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $90–480
Flights from Charleston International Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $70–390
- Website
- southwest.com
Flights from Charleston International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $85–460
Flights from Charleston International Airport to Chicago Midway International Airport via Nashville
- Ave. Duration
- 4h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Denmark Amtrak Station to Chicago Union Station
- Ave. Duration
- 30h 41m
- Frequency
- Once daily
- Estimated price
- $700–1,200
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $20–30
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Charlotte Bus Station to Toledo Bus Stop
- Ave. Duration
- 13h 40m
- Frequency
- Once daily
- Estimated price
- $95–160
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Toledo to Chicago Union Station
- Ave. Duration
- 4h 22m
- Frequency
- Twice a week
- Website
- Amtrak
- Ave. Duration
- 43 min
- Estimated price
- $120–150
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Booking & Getting There
Orangeburg to Chicago bus services, operated by Flixbus USA, arrive at Charlotte Bus Station.
Chicago is 1h behind Orangeburg. It is currently 8:02 PM in Orangeburg and 7:02 PM in Chicago.
Orangeburg to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Orangeburg to Chicago is 806 miles. It takes approximately 14h 47m to drive from Orangeburg to Chicago.
Book your Orangeburg to Chicago bus tickets online with Omio.
There are 1307+ hotels available in Chicago.