Rome2Rio

How to get fromOrangeburg to Durhamby train (Amtrak), bus (Greyhound, Flixbus), car, taxi, plane, bus (Greyhound), bus, or train

Find Transport to Durham

See all options

There are 7 ways to get from Orangeburg to Durham by train (Amtrak), bus (Greyhound, Flixbus), car, taxi, plane, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Denmark Amtrak Station to Carytrain train Floridian
    7h 10m
    $153–262

  2. Drive 239.7 mi

    cheapest
    1. Drive from Orangeburg to Durhamcar car 239.7 mi
    4h 45m
    $44–64

  3. Bus via Charlotte

    1. Take the bus from Orangeburg to Charlotte Bus Stationbus bus Greyhound US0644S / ...
    2. Take the bus from Charlotte Bus Station to Durhambus bus FlixBus N2471 / ...
    7h 23m
    $57–109

  4. Taxi, fly

    1. Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi taxi
    2. Fly from Columbia (CAE) to Raleigh-Durham International Airport (RDU)plane plane CAE - RDU
    5h 22m
    $241–904

  5. Bus (Greyhound)

    1. Take the bus from Orangeburg to Raleigh Bus Stationbus bus Greyhound US0645S
    7h 43m
    $56–101

  6. Bus #2

    1. Take the bus from Orangeburg to Camdenbus bus Greyhound US0644S
    2. Take the bus from Camden to Durhambus bus Augusta
    7h 48m
    $62–96

  7. Bus, train

    1. Take the bus from Orangeburg to Charlotte Bus Stationbus bus Greyhound US0644S / ...
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train Piedmont / ...
    7h 56m
    $82–170

Columbia (CAE) to Raleigh-Durham International Airport (RDU) flights

Calendar155Weekly Planes
Duration4h 20mAverage Duration
Ticket$112Cheapest Price
See schedules

Questions & Answers

Map of how to get from Orangeburg to Durham.ExpandLaunch map view
  • Distance: 283.7 mi
  • Duration: 7h 10m

What companies run services between Orangeburg, SC, USA and Durham, NC, USA?

Amtrak operates a train from Denmark Amtrak Station to Cary once daily. Tickets cost $80–170 and the journey takes 5h 20m. Alternatively, you can take a vehicle from Orangeburg to Durham via Orangeburg and Charlotte Bus Station in around 7h 23m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers