There are 5 ways to get from Orangeburg to Gainesville by bus (Flixbus, Greyhound), train, bus, car, taxi, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Orangeburg to Jacksonvillebus FlixBus 2433
- Take the bus from Jacksonville to Gainesvillebus FlixBus 2431
7h 12m$53–90Train, bus
- Take the train from Denmark Amtrak Station to Jacksonvilletrain Floridian
- Take the bus from Jacksonville to Gainesvillebus FlixBus 2431
8h 56m$134–239Drive 302.3 mi
- Drive from Orangeburg to Gainesvillecar 302.3 mi
5h 40m$56–80Taxi to Columbia, fly
- Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi
- Fly from Columbia (CAE) to Gainesville Regional Airport (GNV)plane CAE - GNV
5h 25m$182–510Drive to Augusta Regional Airport At Bush Field, fly
- Drive from Orangeburg to Augusta Regional Airport At Bush Field (AGS)car
- Fly from Augusta Regional Airport At Bush Field (AGS) to Gainesville Regional Airport (GNV)plane AGS - GNV
6h 28m$71–372
Columbia (CAE) to Gainesville Regional Airport (GNV) flights
Comparing Your Travel Options
The cheapest way to get from Orangeburg to Gainesville is to bus which costs $50 - $95 and takes 7h 12m.
The fastest way to get from Orangeburg to Gainesville is to taxi and fly which takes 5h 25m and costs $180 - $550.
No, there is no direct bus from Orangeburg to Gainesville. However, there are services departing from Orangeburg and arriving at Gainesville via Jacksonville. The journey, including transfers, takes approximately 7h 12m.
The distance between Orangeburg and Gainesville is 319 miles. The road distance is 304 miles.
The best way to get from Orangeburg to Gainesville without a car is to bus which takes 7h 12m and costs $50 - $95.
It takes approximately 7h 12m to get from Orangeburg to Gainesville, including transfers.
Orangeburg to Gainesville bus services, operated by Flixbus USA, depart from Orangeburg station.
Orangeburg to Gainesville bus services, operated by Flixbus USA, arrive at Jacksonville station.
Yes, the driving distance between Orangeburg to Gainesville is 304 miles. It takes approximately 5h 40m to drive from Orangeburg to Gainesville.
Book your Orangeburg to Gainesville bus tickets online with Omio.
What companies run services between Orangeburg, SC, USA and Gainesville, FL, USA?
You can take a vehicle from Orangeburg to Gainesville via Orangeburg and Jacksonville in around 7h 12m.
- Website
- delta.com
Flights from Columbia to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $60–360
Flights from Augusta Regional Airport At Bush Field to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $55–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Denmark Amtrak Station to Jacksonville
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $55–140
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orangeburg to Jacksonville
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 6 times a week
- Estimated price
- $10–16
- Schedules at
- Flixbus USA
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 6 times a week
- Estimated price
- $10–16
- Schedules at
- Flixbus USA
- Ave. Duration
- 43 min
- Estimated price
- $120–150
Want to know more about travelling around United States
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Booking & Getting There
There are 276+ hotels available in Gainesville.