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How to get fromOrangeburg to Ithacaby taxi, plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound)

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There are 8 ways to get from Orangeburg to Ithaca by taxi, plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Columbia, fly to Ithaca Tompkins Regional Airport

    best
    1. Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi taxi
    2. Fly from Columbia (CAE) to Ithaca Tompkins Regional Airport (ITH)plane plane CAE - ITH
    5h 57m
    $195–538

  2. Drive to Charleston International Airport, fly to Ithaca Tompkins Regional Airport

    cheapest
    1. Drive from Orangeburg to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Ithaca Tompkins Regional Airport (ITH)plane plane CHS - ITH
    6h 27m
    $93–468

  3. Train, bus via Newark

    1. Take the train from Denmark Amtrak Station to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Newark Penn Stationtrain train
    3. Take the bus from Newark Penn Station to Ithacabus bus
    20h 47m
    $508–785

  4. Bus via Charlotte

    1. Take the bus from Orangeburg to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Ithacabus bus
    21h 8m
    $154–274

  5. Drive  769.2 mi

    1. Drive from Orangeburg to Ithacacar car 769.2 mi
    14h 45m
    $141–203

  6. Drive to Charleston International Airport, fly to Syracuse Hancock International Airport, bus

    1. Drive from Orangeburg to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Syracuse Hancock International Airport (SYR)plane plane CHS - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    6h 39m
    $205–1,060

  7. Bus

    1. Take the bus from Orangeburg to Camdenbus bus
    2. Take the bus from Camden to New York, NYbus bus
    3. Take the bus from Port Authority Bus Terminal to Ithacabus bus 246
    23h 10m
    $151–325

  8. Train, bus

    1. Take the train from Denmark Amtrak Station to Washington Union Stationtrain train Floridian
    2. Take the bus from Washington Union Station to Ithacabus bus FlixBus 2682
    23h 40m
    $448–670

Columbia (CAE) to Ithaca Tompkins Regional Airport (ITH) flights

Calendar13Weekly Planes
Duration4hAverage Duration
Ticket$70Cheapest Price
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Comparing Your Travel Options

Map of how to get from Orangeburg to Ithaca.ExpandLaunch map view
  • Distance: 689.4 mi
  • Duration: 5h 57m

What companies run services between Orangeburg, SC, USA and Ithaca, NY, USA?

You can take a vehicle from Orangeburg to Ithaca via Orangeburg, Charlotte Bus Station, and Newark Penn Station in around 21h 8m.

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