Rome2Rio

How to get fromOrangeburg to Milwaukeeby taxi, plane, bus (Greyhound, Flixbus, Amtrak), train (Amtrak), car, or bus

Find Transport to Milwaukee

See all options

There are 7 ways to get from Orangeburg to Milwaukee by taxi, plane, bus (Greyhound, Flixbus, Amtrak), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Columbia, fly to General Mitchell International Airport

    best
    1. Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi taxi
    2. Fly from Columbia (CAE) to General Mitchell International Airport (MKE)plane plane CAE - MKE
    5h 29m
    $228–751

  2. Drive to Augusta Regional Airport At Bush Field, fly to General Mitchell International Airport

    cheapest
    1. Drive from Orangeburg to Augusta Regional Airport At Bush Field (AGS)car car
    2. Fly from Augusta Regional Airport At Bush Field (AGS) to General Mitchell International Airport (MKE)plane plane AGS - MKE
    6h 28m
    $127–623

  3. Bus

    1. Take the bus from Orangeburg to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Chicago Union Stationbus bus
    4. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    26h 39m
    $195–316

  4. Train (Amtrak)

    1. Take the train from Denmark Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    33h 42m
    $408–880

  5. Drive  889.7 mi

    1. Drive from Orangeburg to Milwaukeecar car 889.7 mi
    16h 29m
    $163–235

  6. Taxi to Columbia, fly to Chicago O'Hare International Airport, bus

    1. Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi taxi
    2. Fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD)plane plane CAE - ORD
    3. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 30m
    $189–473

  7. Bus to Charlotte Douglas International Airport, fly to General Mitchell International Airport

    1. Take the bus from Orangeburg to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to General Mitchell International Airport (MKE)plane plane CLT - MKE
    8h 18m
    $139–663

Columbia (CAE) to General Mitchell International Airport (MKE) flights

Calendar144Weekly Planes
Duration5h 37mAverage Duration
Ticket$105Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Orangeburg to Milwaukee.ExpandLaunch map view
  • Distance: 768.2 mi
  • Duration: 5h 29m

What companies run services between Orangeburg, SC, USA and Milwaukee, WI, USA?

You can take a vehicle from Orangeburg to Milwaukee Intermodal Station via Orangeburg, Charlotte Bus Station, Toledo, Chicago Union Station, and Chicago Bus Station in around 26h 39m. Alternatively, you can take a vehicle from Orangeburg to Milwaukee via Denmark Amtrak Station and Chicago Union Station in around 33h 42m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There