There are 8 ways to get from Orangeburg to Milwaukee by taxi, plane, bus (Flixbus, Greyhound, Amtrak), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Columbia, fly to General Mitchell International Airport
best- Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi
- Fly from Columbia (CAE) to General Mitchell International Airport (MKE)plane CAE - MKE
5h 33m$228–751Drive to Augusta Regional Airport At Bush Field, fly to General Mitchell International Airport
cheapest- Drive from Orangeburg to Augusta Regional Airport At Bush Field (AGS)car
- Fly from Augusta Regional Airport At Bush Field (AGS) to General Mitchell International Airport (MKE)plane AGS - MKE
6h 27m$117–623Bus
- Take the bus from Orangeburg to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Toledo Bus Stopbus
- Take the bus from Toledo to Chicago Union Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
25h 24mTrain (Amtrak)
- Take the train from Denmark Amtrak Station to Chicago Union Stationtrain Floridian
- Take the train from Chicago Union Station to Milwaukeetrain Hiawatha Service / ...
33h 42m$813–1,355Drive 889.7 mi
- Drive from Orangeburg to Milwaukeecar 889.7 mi
16h 29m$163–235Taxi to Columbia, fly to Chicago O'Hare International Airport, bus
- Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi
- Fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD)plane CAE - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
5h 36m$196–474Bus to Charlotte Douglas International Airport, fly to General Mitchell International Airport
- Take the bus from Orangeburg to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to General Mitchell International Airport (MKE)plane CLT - MKE
6h 59m$136–658Drive to Charleston International Airport, fly to Chicago O'Hare International Airport, bus
- Drive from Orangeburg to Charleston-Airport-CHScar
- Fly from Charleston International Airport (CHS) to Chicago O'Hare International Airport (ORD)plane CHS - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
6h 18m$529–894
Columbia (CAE) to General Mitchell International Airport (MKE) flights
Comparing Your Travel Options
The cheapest way to get from Orangeburg to Milwaukee is to drive which costs $160 - $240 and takes 16h 29m.
The fastest way to get from Orangeburg to Milwaukee is to taxi and fly which takes 5h 33m and costs $220 - $750.
No, there is no direct bus from Orangeburg to Milwaukee station. However, there are services departing from Orangeburg and arriving at Milwaukee Intermodal Station via Charlotte Bus Station, Toledo and Chicago Bus Station. The journey, including transfers, takes approximately 25h 24m.
No, there is no direct train from Orangeburg station to Milwaukee. However, there are services departing from Denmark Amtrak Station and arriving at Milwaukee via Chicago Union Station. The journey, including transfers, takes approximately 33h 42m.
The distance between Orangeburg and Milwaukee is 773 miles. The road distance is 894.9 miles.
The best way to get from Orangeburg to Milwaukee without a car is to bus which takes 25h 24m and costs .
It takes approximately 5h 33m to get from Orangeburg to Milwaukee, including transfers.
Orangeburg to Milwaukee bus services, operated by Flixbus USA, depart from Orangeburg station.
Orangeburg to Milwaukee train services, operated by Amtrak, depart from Denmark Amtrak Station.
The best way to get from Orangeburg to Milwaukee is to bus which takes 25h 24m and costs . Alternatively, you can train, which costs $800 - $1,400 and takes 33h 42m.
What companies run services between Orangeburg, SC, USA and Milwaukee, WI, USA?
You can take a vehicle from Orangeburg to Milwaukee Intermodal Station via Orangeburg, Charlotte Bus Station, Toledo, Chicago Union Station, and Chicago Bus Station in around 25h 24m. Alternatively, you can take a vehicle from Orangeburg to Milwaukee via Denmark Amtrak Station and Chicago Union Station in around 33h 42m.
- Website
- aa.com
Flights from Columbia to General Mitchell International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $100–600
Flights from Columbia to General Mitchell International Airport via Philadelphia
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $140–700
Flights from Columbia to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $100–600
Flights from Columbia to General Mitchell International Airport via Reagan Washington
- Ave. Duration
- 6h 53m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Augusta Regional Airport At Bush Field to General Mitchell International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $110–600
Flights from Augusta Regional Airport At Bush Field to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 7h 52m
- When
- Sunday
- Estimated price
- $100–600
Flights from Columbia to Chicago O'Hare International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $55–300
Flights from Columbia to Chicago O'Hare International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $55–310
Flights from Charlotte Douglas International Airport to General Mitchell International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $100–600
Flights from Charleston International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 44m
- When
- Every day
- Estimated price
- $65–350
Flights from Charleston International Airport to Chicago O'Hare International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 37m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $65–350
- Website
- delta.com
Flights from Columbia to General Mitchell International Airport via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $110–600
Flights from Columbia to General Mitchell International Airport via New York La Guardia
- Ave. Duration
- 6h 14m
- When
- Saturday
- Estimated price
- $160–750
Flights from Augusta Regional Airport At Bush Field to General Mitchell International Airport via Atlanta
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $110–600
Flights from Columbia to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $60–320
Flights from Charlotte Douglas International Airport to General Mitchell International Airport via Atlanta
- Ave. Duration
- 4h 19m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Charleston International Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $70–370
- Website
- united.com
Flights from Columbia to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $100–600
Flights from Columbia to General Mitchell International Airport via Newark
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $150–750
Flights from Columbia to Chicago O'Hare International Airport
- Ave. Duration
- 2h 22m
- When
- Every day
- Estimated price
- $55–300
Flights from Charlotte Douglas International Airport to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 18m
- When
- Monday to Saturday
- Estimated price
- $100–600
Flights from Charleston International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 39m
- When
- Every day
- Estimated price
- $65–350
- Website
- southwest.com
Flights from Charlotte Douglas International Airport to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 3h 47m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Charlotte Douglas International Airport to General Mitchell International Airport via Nashville
- Ave. Duration
- 3h 58m
- When
- Monday to Wednesday
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Denmark Amtrak Station to Chicago Union Station
- Ave. Duration
- 30h 41m
- Frequency
- Once daily
- Estimated price
- $700–1,200
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Charlotte Bus Station to Toledo Bus Stop
- Ave. Duration
- 13h 40m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $16–24
- Website
- Greyhound
Bus from Chicago to Milwaukee Intermodal Station
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Chicago to Milwaukee Intermodal Station
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $14–21
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Toledo to Chicago Union Station
- Ave. Duration
- 4h 22m
- Frequency
- Twice a week
- Website
- Amtrak
- Ave. Duration
- 43 min
- Estimated price
- $120–150
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Booking & Getting There
Orangeburg to Milwaukee bus services, operated by Flixbus USA, arrive at Charlotte Bus Station.
Milwaukee is 1h behind Orangeburg. It is currently 7:42 AM in Orangeburg and 6:42 AM in Milwaukee.
Orangeburg to Milwaukee train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Orangeburg to Milwaukee is 895 miles. It takes approximately 16h 29m to drive from Orangeburg to Milwaukee.
Book your Orangeburg to Milwaukee bus tickets online with Omio.
There are 249+ hotels available in Milwaukee.








