There are 7 ways to get from Orangeburg to Pittsburgh by car, plane, bus (Flixbus, Greyhound), train (Amtrak), taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Charleston International Airport, fly
best- Drive from Orangeburg to Charleston-Airport-CHScar
- Fly from Charleston International Airport (CHS) to Pittsburgh International Airport (PIT)plane CHS - PIT
4h 26m$98–568Bus to Charlotte Douglas International Airport, fly
cheapest- Take the bus from Orangeburg to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Pittsburgh International Airport (PIT)plane CLT - PIT
7h 9m$97–480Bus
- Take the bus from Orangeburg to Charlotte Bus Stationbus
- Take the bus from Charlotte to Charlestonbus
- Take the bus from Charleston to Cambridgebus
- Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus
15h 58m$104–201Train (Amtrak)
- Take the train from Denmark Amtrak Station to Pittsburgh Amtrak Stationtrain Floridian
21h 8m$528–830Drive 576.5 mi
- Drive from Orangeburg to Pittsburghcar 576.5 mi
9h 54m$106–152Taxi to Columbia, fly
- Take the taxi from Orangeburg to Columbia-Airport-CAEtaxi
- Fly from Columbia (CAE) to Pittsburgh International Airport (PIT)plane CAE - PIT
5h 48m$195–578Train to Savannah, fly
- Take the train from Denmark Amtrak Station to Savannah Stationtrain
- Fly from Savannah (SAV) to Pittsburgh International Airport (PIT)plane SAV - PIT
6h 50m$263–855
Charleston International Airport (CHS) to Pittsburgh International Airport (PIT) flights
Comparing Your Travel Options
The cheapest way to get from Orangeburg to Pittsburgh is to drive which costs $100 - $160 and takes 9h 54m.
The fastest way to get from Orangeburg to Pittsburgh is to drive and fly which takes 4h 26m and costs $95 - $600.
No, there is no direct bus from Orangeburg to Pittsburgh station. However, there are services departing from Orangeburg and arriving at Pittsburgh Intermodal Station via Charlotte, Charleston and Cambridge, OH. The journey, including transfers, takes approximately 15h 58m.
No, there is no direct train from Orangeburg station to Pittsburgh station. However, there are services departing from Denmark Amtrak Station and arriving at Pittsburgh Amtrak Station via . The journey, including transfers, takes approximately 21h 8m.
The distance between Orangeburg and Pittsburgh is 624 miles. The road distance is 579.8 miles.
The best way to get from Orangeburg to Pittsburgh without a car is to bus which takes 15h 58m and costs $100 - $210.
It takes approximately 4h 26m to get from Orangeburg to Pittsburgh, including transfers.
Orangeburg to Pittsburgh bus services, operated by Flixbus USA, depart from Orangeburg station.
Orangeburg to Pittsburgh train services, operated by Amtrak, depart from Denmark Amtrak Station.
The best way to get from Orangeburg to Pittsburgh is to bus which takes 15h 58m and costs $100 - $210. Alternatively, you can train, which costs $500 - $850 and takes 21h 8m.
What companies run services between Orangeburg, SC, USA and Pittsburgh, PA, USA?
You can take a vehicle from Orangeburg to Pittsburgh Intermodal Station via Orangeburg, Charlotte, Charleston, and Cambridge, OH in around 15h 58m. Alternatively, Amtrak operates a train from Denmark Amtrak Station to Pittsburgh Amtrak Station once daily. Tickets cost $460–750 and the journey takes 20h 36m.
- Website
- aa.com
Flights from Charleston International Airport to Pittsburgh International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $85–550
Flights from Charleston International Airport to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 3h 52m
- When
- Sunday
- Estimated price
- $95–550
Flights from Columbia to Pittsburgh International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $70–430
Flights from Columbia to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $80–460
Flights from Columbia to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $95–500
Flights from Columbia to Pittsburgh International Airport via Chicago O'Hare
- Ave. Duration
- 5h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $110–600
Flights from Columbia to Pittsburgh International Airport via New York La Guardia
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $100–550
Flights from Charlotte Douglas International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $65–430
Flights from Savannah to Pittsburgh International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $110–650
- Website
- united.com
Flights from Charleston International Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $95–550
Flights from Columbia to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $80–460
Flights from Columbia to Pittsburgh International Airport via Chicago O'Hare
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $110–600
Flights from Columbia to Pittsburgh International Airport via Newark
- Ave. Duration
- 5h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Charlotte Douglas International Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $75–460
Flights from Savannah to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $120–700
- Website
- delta.com
Flights from Charleston International Airport to Pittsburgh International Airport via Atlanta
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $110–600
Flights from Columbia to Pittsburgh International Airport via Atlanta
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $90–490
Flights from Columbia to Pittsburgh International Airport via New York La Guardia
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Savannah to Pittsburgh International Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $120–700
- Website
- southwest.com
Flights from Charleston International Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 28m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $100–600
Flights from Charlotte Douglas International Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 35m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $80–480
Flights from Savannah to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 58m
- When
- Sunday and Saturday
- Estimated price
- $130–700
Flights from Savannah to Pittsburgh International Airport via Nashville
- Ave. Duration
- 3h 55m
- When
- Sunday
- Estimated price
- $140–750
- Website
- flybreeze.com
Flights from Charleston International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 46m
- When
- Monday, Friday, Thursday, and Sunday
- Estimated price
- $190–1,200
- Website
- allegiantair.com
Flights from Savannah to Pittsburgh International Airport
- Ave. Duration
- 1h 46m
- When
- Monday and Friday
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Denmark Amtrak Station to Pittsburgh Amtrak Station
- Ave. Duration
- 20h 36m
- Frequency
- Once daily
- Estimated price
- $460–750
- Website
- Amtrak
Train from Denmark Amtrak Station to Savannah Station
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $20–30
- Schedules at
- Flixbus USA
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $20–30
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Charlotte to Charleston
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Cambridge, OH to Pittsburgh Intermodal Station
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–27
- Website
- Greyhound
Bus from Orangeburg to Charlotte Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charlotte to Charleston
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $28–75
- Website
- Barons Bus
Bus from Charleston to Cambridge
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $14–55
- Website
- Barons Bus
- Ave. Duration
- 43 min
- Estimated price
- $120–150
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Booking & Getting There
Orangeburg to Pittsburgh bus services, operated by Flixbus USA, arrive at Charlotte Bus Station.
Orangeburg to Pittsburgh train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.
Yes, the driving distance between Orangeburg to Pittsburgh is 580 miles. It takes approximately 9h 54m to drive from Orangeburg to Pittsburgh.
Book your Orangeburg to Pittsburgh bus tickets online with Omio.
There are 734+ hotels available in Pittsburgh.










