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How to get fromOregon to Knoxvilleby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 9 ways to get from Oregon to Knoxville by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rogue Valley International - Medford Airport to Mcghee Tyson Airport

    best
    1. Fly from Rogue Valley International - Medford Airport (MFR) to Mcghee Tyson Airport (TYS)plane plane MFR - TYS
    7h 32m
    $288–985

  2. Fly Portland International Airport to Nashville, drive

    cheapest
    1. Fly from Portland International Airport (PDX) to Nashville (BNA)plane plane PDX - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 56m
    $193–753

  3. Bus

    1. Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus bus
    2. Take the bus from Pasco Bus Stop to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to New York Midtownbus bus
    5. Take the bus from New York to Knoxvillebus bus
    3d 8h
    $697–1,198

  4. Train, bus via Chicago

    1. Take the train from Portland to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 8h
    $1,187–2,292

  5. Drive 2,495.3 mi

    1. Drive from Portland to Knoxvillecar car 2,495.3 mi
    40h 34m
    $456–658

  6. Fly Portland International Airport to Mcghee Tyson Airport

    1. Fly from Portland International Airport (PDX) to Mcghee Tyson Airport (TYS)plane plane PDX - TYS
    8h 24m
    $348–1,273

  7. Fly Mahlon Sweet Field Airport to Mcghee Tyson Airport

    1. Fly from Mahlon Sweet Field Airport (EUG) to Mcghee Tyson Airport (TYS)plane plane EUG - TYS
    7h 45m
    $336–1,176

  8. Fly Roberts Field-Redmond Municipal Airport to Mcghee Tyson Airport

    1. Fly from Roberts Field-Redmond Municipal Airport (RDM) to Mcghee Tyson Airport (TYS)plane plane RDM - TYS
    9h 26m
    $297–1,078

  9. Train, bus

    1. Take the train from Portland to Vancouvertrain train
    2. Take the train from Vancouver to Toronto Union Stationtrain train
    3. Take the train from Toronto Union Station to New York Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus
    5d 8h
    $1,132–2,301

Rogue Valley International - Medford Airport (MFR) to Mcghee Tyson Airport (TYS) flights

Calendar17Weekly Planes
Duration8h 52mAverage Duration
Ticket$229Cheapest Price
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Questions & Answers

Map of how to get from Oregon to Knoxville.ExpandLaunch map view
  • Distance: 2,130.9 mi
  • Duration: 7h 32m

What companies run services between Oregon, USA and Knoxville, TN, USA?

United Airlines, Allegiant Air, and American Airlines fly from Rogue Valley International - Medford Airport (MFR) to Mcghee Tyson Airport (TYS) twice daily. Alternatively, you can take a bus from Portland Curbside Bus Stop to Knoxville via Pasco Bus Stop, Denver Union Station, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 3d 8h.

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