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How to get fromOrlando Airport (MCO) to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Des Moines

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There are 5 ways to get from Orlando Airport (MCO) to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Orlando (MCO) to Des Moines (DSM)plane plane MCO - DSM
    5h 11m
    $175–753

  2. Bus

    1. Take the bus from Orlando to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    33h 3m
    $207–402

  3. Train, bus

    1. Take the train from Winter Park Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    2d
    $554–1,199

  4. Drive 1,329.3 mi

    1. Drive from Orlando Airport (MCO) to Des Moinescar car 1,329.3 mi
    23h 3m
    $243–351

  5. Fly to Omaha, bus

    1. Fly from Orlando (MCO) to Omaha (OMA)plane plane MCO - OMA
    2. Take the bus from Omaha, NE to Des Moinesbus bus
    7h 53m
    $218–642

Orlando Airport (MCO) to Des Moines by bus

Calendar6Weekly Buses
Duration33h 3mAverage Duration
Ticket$207Cheapest Price
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Questions & Answers

Map of how to get from Orlando Airport (MCO) to Des Moines.ExpandLaunch map view
  • Distance: 1,147.4 mi
  • Duration: 5h 11m

What companies run services between Orlando Airport (MCO), USA and Des Moines, IA, USA?

Delta, Southwest Airlines, and two other airlines fly from Orlando (MCO) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Orlando International Airport to Des Moines via Florida Mall, Orlando, Atlanta Bus Station, and St Louis Bus Station in around 33h 3m.

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