There are 9 ways to get from Orlando, FL to Key West, FL by plane, train, bus, shuttle, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando Sanford to Key West International Airport
best- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
3h 5m$174–425Bus
cheapest- Take the bus from Orlando to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus Lks
13h 4m$54–96Train, bus, shuttle
- Take the train from Orlando to Miamitrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take a shuttle bus from Big Pine Key, FL to Key West, FL
10h 35m$187–358Train, bus
- Take the train from Orlando to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus Lks
13h 14m$87–194Drive 371.4 mi
- Drive from Orlando, FL to Key West, FLcar 371.4 mi
7h 47m$68–98Fly Orlando to Key West International Airport
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
4h 14m$144–745Fly Orlando to Miami International Airport, shuttle
- Fly from Orlando (MCO) to Miami International Airport (MIA)plane MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
7h 46m$774–1,305Train to Tampa, fly to Key West International Airport
- Take the train from Orlando to Tampatrain
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
6h 54m$153–481Bus, shuttle
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Key West, FLTo the Keys
10h 58m$227–282
Orlando, FL to Key West, FL by train, bus, and foot
Comparing Your Travel Options
The cheapest way to get from Orlando, FL to Key West, FL is to bus which costs $50 - $100 and takes 13h 4m.
The fastest way to get from Orlando, FL to Key West, FL is to fly which takes 3h 5m and costs $170 - $430.
No, there is no direct bus from Orlando, FL to Key West, FL. However, there are services departing from S Orange Ave & Sturtevant St and arriving at Whitehead & Eaton via Orlando, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 13h 4m.
The distance between Orlando, FL and Key West, FL is 321 miles. The road distance is 373.6 miles.
The best way to get from Orlando, FL to Key West, FL without a car is to train and bus and shuttle which takes 10h 35m and costs $180 - $360.
It takes approximately 3h 5m to get from Orlando, FL to Key West, FL, including transfers.
Orlando, FL to Key West, FL bus services, operated by Flixbus USA, depart from Orlando station.
The best way to get from Orlando, FL to Key West, FL is to fly which takes 3h 5m and costs $170 - $430. Alternatively, you can bus, which costs $50 - $100 and takes 13h 4m.
Orlando, FL to Key West, FL bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Orlando, FL to Key West, FL is 374 miles. It takes approximately 7h 47m to drive from Orlando, FL to Key West, FL.
What companies run services between Orlando, FL, USA and Key West, FL, USA?
Allegiant Air flies from Orlando Sanford (SFB) to Key West International Airport (EYW) 4 times a week. Alternatively, you can take a vehicle from Orlando, FL to Whitehead & Eaton via S Orange Ave & Sturtevant St, Florida Mall, Orlando, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 13h 4m.
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- $35–250
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $40–280
- Phone
- +1 831-539-2901
- [email protected]
- Website
- gobrightline.com
Train from Orlando to Miami
- Ave. Duration
- 3h 36m
- Frequency
- Every 2 hours
- Estimated price
- $40–170
- Book at
- Brightline
- Smart
- $40–90
- Premium
- $110–170
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
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Booking & Getting There
There are 964+ hotels available in Key West, FL.




