There are 6 ways to get from Orlando, FL to South Carolina by plane, taxi, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando Sanford to Asheville Regional Airport, taxi
best- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Take the taxi from Asheville-Airport-AVL to Greenvilletaxi
3h 14m$259–585Drive 378.7 mi
cheapest- Drive from Orlando, FL to Charlestoncar 378.7 mi
6h 32m$70–100Train (Amtrak)
- Take the train from Orlando to Charleston Amtrak Stationtrain Silver Meteor
8h 2m$157–301Fly Orlando to Charlotte Douglas International Airport, taxi
- Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane MCO - CLT
- Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi
3h 59m$184–445Fly Orlando to Charleston International Airport
- Fly from Orlando (MCO) to Charleston International Airport (CHS)plane MCO - CHS
4h 8m$71–257Fly Orlando Sanford to Greenville–Spartanburg International Airport
- Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane SFB - GSP
2h 23m$179–610
Orlando Sanford (SFB) to Asheville Regional Airport (AVL) flights
Questions & Answers
The cheapest way to get from Orlando, FL to South Carolina is to drive which costs $65 - $100 and takes 6h 32m.
The fastest way to get from Orlando, FL to South Carolina is to fly which takes 2h 23m and costs $170 - $650.
No, there is no direct train from Orlando, FL to South Carolina station. However, there are services departing from Orlando and arriving at Charleston Amtrak Station via . The journey, including transfers, takes approximately 8h 2m.
The distance between Orlando, FL and South Carolina is 541 miles. The road distance is 380.9 miles.
The best way to get from Orlando, FL to South Carolina without a car is to train which takes 8h 2m and costs $150 - $310.
It takes approximately 3h 14m to get from Orlando, FL to South Carolina, including transfers.
Orlando, FL to South Carolina train services, operated by Amtrak, depart from Orlando station.
The best way to get from Orlando, FL to South Carolina is to train which takes 8h 2m and costs $150 - $310. Alternatively, you can fly, which costs $70 - $260 and takes 4h 8m.
Orlando, FL to South Carolina train services, operated by Amtrak, arrive at Charleston Amtrak Station.
Yes, the driving distance between Orlando, FL to South Carolina is 381 miles. It takes approximately 6h 32m to drive from Orlando, FL to South Carolina.
What companies run services between Orlando, FL, USA and South Carolina, USA?
Amtrak operates a train from Orlando to Charleston Amtrak Station once daily. Tickets cost $120–270 and the journey takes 7h 49m. Alternatively, Breeze Airways flies from Orlando (MCO) to Charleston International Airport (CHS) once daily.
- Website
- aa.com
Flights from Orlando to Charlotte Douglas International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $80–460
- Website
- allegiantair.com
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $55–340
Flights from Orlando Sanford to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 28m
- When
- Thursday and Sunday
- Estimated price
- $80–490
- Website
- flyfrontier.com
Flights from Orlando to Charlotte Douglas International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $100–340
- Website
- delta.com
Flights from Orlando to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $95–500
- Website
- flybreeze.com
Flights from Orlando to Charleston International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $65–250
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Charleston Amtrak Station
- Ave. Duration
- 7h 49m
- Frequency
- Once daily
- Estimated price
- $120–270
- Website
- Amtrak
- Ave. Duration
- 47 min
- Estimated price
- $80–170
Asheville Taxi
- Phone
- +1 828-333-1976
- Website
- avltaxi.com
Charlotte Taxi Service
- Phone
- +1 704-464-9191
- Website
- charlottetaxiservice.com
Crown Cab Charlotte
- Phone
- +1 704-334-6666
- Website
- crowncabinc.com
Yellow Cab of Charlotte
- Phone
- +1 704-444-4444
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There are 1910+ hotels available in South Carolina.



