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How to get fromOrlando Health/Amtrak to Louisvilleby plane, bus (Flixbus, Greyhound, Amtrak), car, or train

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There are 6 ways to get from Orlando Health/Amtrak to Louisville by plane, bus (Flixbus, Greyhound, Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Louisville International Airport

    best
    1. Fly from Orlando (MCO) to Louisville International Airport (SDF)plane plane MCO - SDF
    4h 58m
    $395–908

  2. Bus

    cheapest
    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    18h 27m
    $134–259

  3. Drive 813.1 mi

    1. Drive from Orlando Health/Amtrak to Louisvillecar car 813.1 mi
    14h 38m
    $149–215

  4. Fly Orlando Sanford to Louisville International Airport

    1. Fly from Orlando Sanford (SFB) to Louisville International Airport (SDF)plane plane SFB - SDF
    3h 52m
    $164–678

  5. Fly Orlando Sanford to Blue Grass Airport, drive

    1. Fly from Orlando Sanford (SFB) to Blue Grass Airport (LEX)plane plane SFB - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    3h 54m
    $226–894

  6. Train to Tampa, fly to Louisville International Airport

    1. Take the train from Orlando to Tampatrain train
    2. Fly from Tampa (TPA) to Louisville International Airport (SDF)plane plane TPA - SDF
    7h 41m
    $266–670

Orlando Health/Amtrak to Louisville by train and bus

Calendar14Weekly Services
Duration18h 27mAverage Duration
Ticket$134Cheapest Price
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Questions & Answers

Map of how to get from Orlando Health/Amtrak to Louisville.ExpandLaunch map view
  • Distance: 749.1 mi
  • Duration: 4h 58m

What companies run services between Orlando Health/Amtrak, FL, USA and Louisville, KY, USA?

Southwest Airlines, Delta, and American Airlines fly from Orlando (MCO) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a train from Orlando Health/Amtrak to Louisville, KY via LYNX Central, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, Atlanta Bus Station, and Nashville in around 18h 27m.

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