There are 10 ways to get from Orlando to Big Pine Key by plane, bus, shuttle, train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Key West International Airport, bus
best- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
- Take the bus from Key West Airport to Big Pine Keybus
4h 18m$72–710Bus
cheapest- Take the bus from Orlando to Miami Airport Stationbus FlixBus 2411 / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
10h 14m$60–92Bus, shuttle
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLTo the Keys
8h 25m$208–259Train, bus via Pembroke Pines
- Take the train from Orlando to Hollywood Amtrak Stationtrain Silver Meteor / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
10h 49m$163–252Drive 341.6 mi
- Drive from Orlando to Big Pine Keycar 341.6 mi
7h$61–88Fly Orlando Sanford to Key West International Airport, bus
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
- Take the bus from Key West Airport to Big Pine Keybus
3h 34m$101–321Fly Orlando to Miami International Airport, shuttle
- Fly from Orlando (MCO) to Miami International Airport (MIA)plane MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
6h 25m$752–1,282Fly Orlando to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)plane MCO - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
6h 50m$482–1,052Bus to Tampa, fly to Key West International Airport, bus
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
- Take the bus from Key West Airport to Big Pine Keybus
6h 29m$65–204Train, bus
- Take the train from Orlando to Miamitrain Blfm
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
10h 39m$89–245
Orlando to Big Pine Key by bus and shuttle
Comparing Your Travel Options
The cheapest way to get from Orlando to Big Pine Key is to drive which costs $60 - $90 and takes 7h.
The fastest way to get from Orlando to Big Pine Key is to fly and bus which takes 3h 34m and costs $100 - $330.
No, there is no direct bus from Orlando to Big Pine Key. However, there are services departing from Mccoy Rd & Gondola Dr and arriving at Big Pine Key via Orlando and Miami Airport Station. The journey, including transfers, takes approximately 10h 14m.
The distance between Orlando and Big Pine Key is 316 miles. The road distance is 343.6 miles.
The best way to get from Orlando to Big Pine Key without a car is to bus and shuttle which takes 8h 25m and costs $200 - $260.
It takes approximately 4h 18m to get from Orlando to Big Pine Key, including transfers.
Orlando to Big Pine Key bus services, operated by Flixbus USA, depart from Orlando station.
Orlando to Big Pine Key bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Orlando to Big Pine Key is 344 miles. It takes approximately 7h to drive from Orlando to Big Pine Key.
Book your Orlando to Big Pine Key bus tickets online with Omio.
What companies run services between Orlando, FL, USA and Big Pine Key, FL, USA?
You can take a bus from Mccoy Rd & Gondola Dr to Big Pine Key via Florida Mall, Orlando, and Miami Airport Station in around 10h 14m.
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $35–230
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $35–260
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $35–260
Flights from Orlando to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $40–300
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 23m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $65–700
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $45–170
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 20m
- When
- Friday, Monday, Thursday, and Sunday
- Estimated price
- $35–240
- Website
- jetblue.com
Flights from Orlando to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $40–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Hollywood Amtrak Station
- Ave. Duration
- 5h 2m
- Frequency
- Twice daily
- Estimated price
- $130–220
- Website
- Amtrak
- Phone
- +1 831-539-2901
- [email protected]
- Website
- gobrightline.com
Train from Orlando to Miami
- Ave. Duration
- 3h 36m
- Frequency
- Every 2 hours
- Estimated price
- $40–170
- Book at
- Brightline
- Smart
- $40–90
- Premium
- $110–170
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Key West Airport to Big Pine Key
- Ave. Duration
- 40 min
- Frequency
- 3 times a day
- Estimated price
- $5–8
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- Greyhound
Bus from Key West Airport to Big Pine Key
- Ave. Duration
- 40 min
- Frequency
- 3 times a day
- Estimated price
- $5–8
- Website
- Greyhound
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $15–23
- Website
- Greyhound
Bus from Key West Airport to Big Pine Key
- Ave. Duration
- 40 min
- Frequency
- 3 times a day
- Estimated price
- $5–8
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- Greyhound
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Orlando - RedCoach Station, FL to Miami Airport
- Ave. Duration
- 4h 25m
- Frequency
- 4 times a day
- Estimated price
- $55–80
- Website
- RedCoach
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
Bus from Orlando to Miami Airport Station
- Ave. Duration
- 4h 20m
- Frequency
- Every 4 hours
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
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Booking & Getting There
There are 113+ hotels available in Big Pine Key.













