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How to get fromOrlando to Cape Girardeauby plane, bus, taxi, car, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Orlando to Cape Girardeau by plane, bus, taxi, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Lambert–St. Louis International Airport, bus

    best
    1. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 32m
    $209–419

  2. Bus

    cheapest
    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    20h 29m
    $156–300

  3. Bus, taxi

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    17h 36m
    $242–386

  4. Drive 884.2 mi

    1. Drive from Orlando to Cape Girardeaucar car 884.2 mi
    15h
    $162–234

  5. Fly Orlando Sanford to Midamerica St. Louis Airport, bus

    1. Fly from Orlando Sanford (SFB) to Midamerica St. Louis Airport (BLV)plane plane SFB - BLV
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 10m
    $191–569

  6. Fly Orlando to Memphis, bus

    1. Fly from Orlando (MCO) to Memphis (MEM)plane plane MCO - MEM
    2. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    8h 57m
    $397–917

  7. Fly Orlando to Nashville, bus, taxi

    1. Fly from Orlando (MCO) to Nashville (BNA)plane plane MCO - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    9h 44m
    $374–944

  8. Bus to Tampa, fly to Lambert–St. Louis International Airport, bus

    1. Take the bus from Orlando Bus Station to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    9h 47m
    $462–2,074

Orlando (MCO) to Lambert–St. Louis International Airport (STL) flights

Calendar66Weekly Planes
Duration3h 2mAverage Duration
Ticket$113Cheapest Price
See schedules

Questions & Answers

Map of how to get from Orlando to Cape Girardeau.ExpandLaunch map view
  • Distance: 1,027.8 mi
  • Duration: 7h 32m

What companies run services between Orlando, FL, USA and Cape Girardeau, MO, USA?

You can take a bus from Orlando Bus Station to Cape Girardeau via Atlanta Bus Station, Memphis Bus Station, and Cape Girardeau in around 20h 29m.

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Bus operators
Other operators

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