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How to get fromOrlando to Defianceby plane, taxi, bus (Flixbus, Greyhound, Amtrak), train (Amtrak), car, bus, or train

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There are 9 ways to get from Orlando to Defiance by plane, taxi, bus (Flixbus, Greyhound, Amtrak), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando Sanford to Toledo, taxi

    best
    1. Fly from Orlando Sanford (SFB) to Toledo (TOL)plane plane SFB - TOL
    2. Take the taxi from Toledo (TOL) to Defiancetaxi taxi
    3h 51m
    $256–643

  2. Drive 1,040.9 mi

    cheapest
    1. Drive from Orlando to Defiancecar car 1,040.9 mi
    18h 12m
    $190–275

  3. Bus

    1. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Bryan Amtrak Stationbus bus
    27h
    $246–411

  4. Train (Amtrak)

    1. Take the train from Orlando to Toledotrain train Floridian
    2. Take the train from Toledo to Bryan Amtrak Stationtrain train Lake Shore Limited
    36h 38m
    $557–1,061

  5. Fly Orlando Sanford to Fort Wayne International Airport, taxi

    1. Fly from Orlando Sanford (SFB) to Fort Wayne International Airport (FWA)plane plane SFB - FWA
    2. Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi taxi
    4h 3m
    $286–673

  6. Fly Orlando to John Glenn Columbus International Airport, bus, taxi

    1. Fly from Orlando (MCO) to John Glenn Columbus International Airport (CMH)plane plane MCO - CMH
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    8h 45m
    $307–1,292

  7. Fly Orlando to Cleveland-Hopkins International Airport, train

    1. Fly from Orlando (MCO) to Cleveland-Hopkins International Airport (CLE)plane plane MCO - CLE
    2. Take the train from Cleveland Amtrak to Bryan Amtrak Stationtrain train
    9h 30m
    $220–785

  8. Fly Orlando to Indianapolis, bus, taxi

    1. Fly from Orlando (MCO) to Indianapolis (IND)plane plane MCO - IND
    2. Take the bus from Indianapolis, IN to Fort Wayne, INbus bus
    3. Take the taxi from Fort Wayne, IN to Defiancetaxi taxi
    9h 6m
    $324–620

  9. Fly Orlando to Detroit, bus, train

    1. Fly from Orlando (MCO) to Detroit (DTW)plane plane MCO - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    9h 35m
    $311–794

Orlando Sanford (SFB) to Toledo (TOL) flights

Calendar2Weekly Planes
Duration2h 23mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Orlando to Defiance.ExpandLaunch map view
  • Distance: 963.2 mi
  • Duration: 3h 51m

What companies run services between Orlando, FL, USA and Defiance, OH, USA?

You can take a bus from Orlando Bus Station to Defiance via Charlotte Bus Station, Toledo, and Bryan Amtrak Station in around 27h. Alternatively, you can take a train from Orlando to Defiance via Toledo and Bryan Amtrak Station in around 36h 38m.

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