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How to get fromOrlando to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Des Moines

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There are 5 ways to get from Orlando to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Orlando Sanford

    best
    1. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    3h 41m
    $174–576

  2. Fly from Orlando

    cheapest
    1. Fly from Orlando (MCO) to Des Moines (DSM)plane plane MCO - DSM
    6h 19m
    $115–485

  3. Bus

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    30h 55m
    $226–369

  4. Train, bus

    1. Take the train from Orlando to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    46h 34m
    $519–1,273

  5. Drive  1,319.3 mi

    1. Drive from Orlando to Des Moinescar car 1,319.3 mi
    22h 51m
    $241–348

Orlando to Des Moines by bus

Calendar7Weekly Buses
Duration30h 55mAverage Duration
Ticket$226Cheapest Price
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Comparing Your Travel Options

Map of how to get from Orlando to Des Moines.ExpandLaunch map view
  • Distance: 1,151.4 mi
  • Duration: 3h 41m

What companies run services between Orlando, FL, USA and Des Moines, IA, USA?

Allegiant Air flies from Orlando Sanford (SFB) to Des Moines (DSM) 4 times a week. Alternatively, you can take a bus from Orlando Bus Station to Des Moines via Atlanta Bus Station and Indianapolis Union Station in around 30h 55m.

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Need to know: Greyhound

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