There are 6 ways to get from Orlando to Durham by plane, bus (Flixbus), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Raleigh-Durham International Airport
best- Fly from Orlando (MCO) to Raleigh-Durham International Airport (RDU)plane MCO - RDU
4h 28m$68–218Bus (Flixbus)
- Take the bus from Orlando Bus Station to Raleigh Bus Stationbus FlixBus N2472
12h 40m$93–141Train (Amtrak)
- Take the train from Orlando to Carytrain Floridian
14h 52m$156–371Drive 595.7 mi
- Drive from Orlando to Durhamcar 595.7 mi
10h 31m$109–157Fly Orlando to Piedmont Triad International Airport, train
- Fly from Orlando (MCO) to Piedmont Triad International Airport (GSO)plane MCO - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
5h 21m$129–1,172Bus to Tampa, fly to Raleigh-Durham International Airport
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Raleigh-Durham International Airport (RDU)plane TPA - RDU
6h 49m$95–479
Orlando to Durham by bus (Flixbus)
Comparing Your Travel Options
The cheapest way to get from Orlando to Durham is to fly which costs $65 - $220 and takes 4h 28m.
The fastest way to get from Orlando to Durham is to fly which takes 4h 28m and costs $65 - $220.
No, there is no direct bus from Orlando station to Durham. However, there are services departing from Orlando Bus Station and arriving at Durham via Raleigh Bus Station. The journey, including transfers, takes approximately 12h 40m.
No, there is no direct train from Orlando to Durham station. However, there are services departing from Orlando and arriving at Durham Amtrak Station via Cary. The journey, including transfers, takes approximately 14h 52m.
The distance between Orlando and Durham is 572 miles. The road distance is 599.2 miles.
The best way to get from Orlando to Durham without a car is to bus which takes 12h 40m and costs $90 - $150.
It takes approximately 4h 28m to get from Orlando to Durham, including transfers.
Orlando to Durham bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Orlando to Durham train services, operated by Amtrak, depart from Orlando station.
The best way to get from Orlando to Durham is to fly which takes 4h 28m and costs $65 - $220. Alternatively, you can bus, which costs $90 - $150 and takes 12h 40m, you could also train, which costs $150 - $380 and takes 14h 52m.
What companies run services between Orlando, FL, USA and Durham, NC, USA?
Frontier Airlines, Breeze Airways, and two other airlines fly from Orlando (MCO) to Raleigh-Durham International Airport (RDU) every 2 hours. Alternatively, Flixbus USA operates a bus from Orlando Bus Station to Raleigh Bus Station 5 times a week. Tickets cost $90–140 and the journey takes 11h 5m.
- Website
- delta.com
Flights from Orlando to Raleigh-Durham International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $70–420
Flights from Orlando to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $130–750
Flights from Tampa to Raleigh-Durham International Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $75–450
Flights from Tampa to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $90–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Cary
- Ave. Duration
- 13h 34m
- Frequency
- Once daily
- Estimated price
- $150–360
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $13–35
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Raleigh Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- 5 times a week
- Estimated price
- $90–140
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $12–19
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Orlando to Durham bus services, operated by Flixbus USA, arrive at Raleigh Bus Station.
Orlando to Durham train services, operated by Amtrak, arrive at Cary station.
Yes, the driving distance between Orlando to Durham is 599 miles. It takes approximately 10h 31m to drive from Orlando to Durham.
Book your Orlando to Durham train tickets online with Omio.
Book your Orlando to Durham bus tickets online with Omio and FlixBus.
There are 398+ hotels available in Durham.