There are 4 ways to get from Orlando to Florence by plane, train (Amtrak), bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Orlando (MCO) to Florence Regional Airport (FLO)plane MCO - FLO
5h 31m$72–345Train (Amtrak)
- Take the train from Orlando to Florence Stationtrain Silver Meteor
9h 46m$160–330Bus
- Take the bus from Orlando Bus Station to Jacksonvillebus
- Take the bus from Jacksonville to Sumter Bus Stopbus
- Take the bus from Sumter Bus Stop to Florence Bus Stationbus
11h 45m$74–146Drive 446.5 mi
- Drive from Orlando to Florencecar 446.5 mi
7h 22m$82–118
Orlando to Florence by train (Amtrak)
Questions & Answers
The cheapest way to get from Orlando to Florence is to bus which costs $70 - $150 and takes 11h 45m.
The fastest way to get from Orlando to Florence is to fly which takes 5h 31m and costs $70 - $350.
No, there is no direct bus from Orlando station to Florence station. However, there are services departing from Orlando Bus Station and arriving at Florence Bus Station via Jacksonville and Sumter Bus Stop. The journey, including transfers, takes approximately 11h 45m.
Yes, there is a direct train departing from Orlando and arriving at Florence Station station. Services depart once daily, and operate every day. The journey takes approximately 9h 46m.
The distance between Orlando and Florence is 430 miles. The road distance is 449.2 miles.
The best way to get from Orlando to Florence without a car is to train which takes 9h 46m and costs $160 - $330.
It takes approximately 5h 31m to get from Orlando to Florence, including transfers.
Orlando to Florence bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Orlando to Florence train services, operated by Amtrak, depart from Orlando station.
The best way to get from Orlando to Florence is to fly which takes 5h 31m and costs $70 - $350. Alternatively, you can train, which costs $160 - $330 and takes 9h 46m, you could also bus, which costs $70 - $150 and takes 11h 45m.
What companies run services between Orlando, FL, USA and Florence, SC, USA?
American Airlines and Frontier Airlines fly from Orlando (MCO) to Florence Regional Airport (FLO) 3 times a day. Alternatively, Amtrak operates a train from Orlando to Florence Station once daily. Tickets cost $160–330 and the journey takes 9h 46m.
- Website
- aa.com
Flights from Orlando to Florence Regional Airport via Charlotte
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $60–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Florence Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $160–330
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando Bus Station to Jacksonville
- Ave. Duration
- 2h 40m
- Frequency
- 5 times a day
- Estimated price
- $23–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jacksonville to Sumter Bus Stop
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
Bus from Sumter Bus Stop to Florence Bus Station
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $6–12
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Orlando to Florence bus services, operated by Flixbus USA, arrive at Jacksonville station.
Orlando to Florence train services, operated by Amtrak, arrive at Florence Station.
Yes, the driving distance between Orlando to Florence is 449 miles. It takes approximately 7h 22m to drive from Orlando to Florence.
Book your Orlando to Florence train tickets online with Omio.
Book your Orlando to Florence bus tickets online with Omio and FlixBus.
There are 49+ hotels available in Florence.